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A patient presented with a rare case of bilateral gluteal compartment syndrome. A 39-year-old male, who experienced unconsciousness in a sitting position attributable to a drug overdose, suffered from right dominant bilateral gluteal compartment syndrome with bilateral leg paralysis due to sciatic nerve palsy, involving rhabdomyolysis and acute renal failure. Since the pressure in the right gluteus maximus compartment in the buttocks was recorded as 20 mmHg, he was administered conservative treatment. Within 12 months, he recovered his ability to walk; however, right foot paralysis and right sciatic nerve irritation were observed to persist.
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