The present article describes the analysis of an n-hexane soluble fraction of fresh flowers of Azadirachta indica A. Juss (Neem), possessing larvicidal activity against Anopheles stephensi Liston, a vector of malarial parasite. Forty-one compounds were identified in non-polar to less-polar fraction as well as in essential oil. These identifications were basically made through GC-EIMS. Thus 5 sesquiterpenes, 3 aromatics, 17 fatty acids, 5 fatty acid esters, three steroids and 8 hydrocarbons were identified. The compounds 1-5, 10, 14-17, 21a and 36-38 were reported previously from different parts of the tree including flowers. The rest of the compounds are reported for the first time from flowers.
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http://dx.doi.org/10.1080/14786410802006082 | DOI Listing |
Nat Prod Res
December 2024
Technical and Applied Chemistry Department, Veermata Jijabai Technological Institute, Matunga, Mumbai, Maharashtra, India.
Adv Mind Body Med
October 2024
It is no surprise that nature has provided us with many therapeutic compounds for thousands of years. Throughout history, plants and their derivatives have been used orally and locally to treat most of the diseases. In addition to providing a wealth of health benefits, Azadirachta indica stands out among all of them as one of the most universal and prolific trees.
View Article and Find Full Text PDFACS Appl Mater Interfaces
May 2024
Department of Metallurgical and Materials Engineering, Indian Institute of Technology Kharagpur, Kharagpur 721302, India.
In the field of bone tissue engineering, recently developed Zn alloy scaffolds are considered potential candidates for biodegradable implants for bone regeneration and defect reconstruction. However, the clinical success of these alloys is limited due to their insufficient surface bioactivities. Further, the higher concentration of Zn produced during degradation promotes antibacterial activity, but deteriorates osteogenic properties.
View Article and Find Full Text PDFPersoonia
June 2023
Wasterdijk Fungal Biodiversity Institute, P.O. Box 85167, 3508 AD Utrecht, The Netherlands.
Food Nutr Res
March 2024
Department of Anatomy, College of Veterinary Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.
Background: Nimbolide, a bioactive compound derived from the neem tree, has garnered attention as a potential breakthrough in the prevention and treatment of chronic diseases. Recent updates in research highlight its multifaceted pharmacological properties, demonstrating anti-inflammatory, antioxidant, and anticancer effects. With a rich history in traditional medicine, nimbolide efficacy in addressing the molecular complexities of conditions such as cardiovascular diseases, diabetes, and cancer positions it as a promising candidate for further exploration.
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