The effects of an intentional infant sign language program on mother-infant interactions were studied. Design was quasi-experimental, longitudinal, descriptive and comparative. The sample was composed of 14 mother-infant dyads, with the infants being between 5 and 9 months at the beginning of the study. The participants were middle or upper-middle socio-economic status. The interactions were evaluated through observations of free play and analyzed using a Grid to analyze early interactions. The frequency and duration of synchronic interactions were compared across experimental and control groups at 12-14 and 18-20 months of age using non-parametric Mann-Whitney tests. The results suggested significant differences between groups on visual and tactile synchronic interactions, and a tendency for vocal interactions, in the direction of higher frequencies in the experimental group.
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http://dx.doi.org/10.1016/j.infbeh.2008.12.011 | DOI Listing |
BMC Infect Dis
December 2024
Institute of Biotechnology, Addis Ababa University P.O.Box.1176, Addis Ababa, Ethiopia.
Background: Early detection and treatment of carbapenem-resistant Klebsiella pneumoniae (CRKP) could reduce the risk of developing life-threatening sepsis in childhood. However, little is known about sepsis caused by CRKP in children under-5 in developing countries. This study aimed to determine the epidemiology, antimicrobial resistance profile, associated risk factors and management of CRKP in children under-5 with sepsis in Ethiopia.
View Article and Find Full Text PDFJ Clin Immunol
December 2024
Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Bologna, Italy.
Background: Activated Phosphoinositide 3-Kinase (PI3K) δ Syndrome (APDS), an inborn error of immunity due to upregulation of the PI3K pathway, leads to recurrent infections and immune dysregulation (lymphoproliferation and autoimmunity).
Methods: Clinical and genetic data of 28 APDS patients from 25 unrelated families were collected from fifteen Italian centers.
Results: Patients were genetically confirmed with APDS-1 (n = 20) or APDS-2 (n = 8), with pathogenic mutations in the PIK3CD or PIK3R1 genes.
Front Immunol
December 2024
Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Background: According to the WHO's recommendation for developing countries, Bacillus Calmette-Guerin (BCG) vaccination has been implemented in some countries as part of national vaccination programs at birth. Although it is generally considered safe, some complications may occur; including BCGitis (local) or BCGosis (systemic), ranging from mild like local abscesses to fatal impediments like osteomyelitis and disseminated BCG infection. This study aimed to determine the spectrum of inborn errors of immunity (IEI) in BCG-vaccinated neonates experiencing local or systemic complications.
View Article and Find Full Text PDFCureus
December 2024
Pediatric Cardiology, Kurashiki Central Hospital, Okayama, JPN.
Capillary refill time (CRT) is a valuable clinical sign in pediatric assessment, particularly in evaluating circulatory status. We present a case of a one-month-old infant with supraventricular tachycardia (SVT), who demonstrated prolonged CRT, emphasizing the importance of this physical examination finding in the context of other signs of compromised circulation.
View Article and Find Full Text PDFBMC Urol
December 2024
Department of Pediatric Surgery, Faculty of Medicine, Istanbul Medeniyet University, Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, Türkiye, Turkey.
Introduction: Spina bifida is a condition that impacts the development of the neural tube leading to urological and gastrointestinal symptoms. Both systems are influenced together due to their shared innervation and embryological origin. Despite its impact on health and well-being there has been limited research on the relationship between manometry results and urodynamic tests, in this patient population.
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