Post-traumatic fibro-osseous lesion is a rare benign osseous lesion usually affecting the ribs and relatively under-recognised. Histologically, it showed a bland fibrous stroma in which resided an anastomosing network of bone trabeculae, having a zonal pattern of maturation from metaplastic woven to mature lamellar bone, with or without an associated xanthomatous component. We report a well-documented case of mixed variant post-traumatic fibro-osseous lesion of the sixth rib, which was initially misdiagnosed as particular form of fibrous dysplasia associated with a xanthoma.
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