Ileal pouch-anal anastomosis has become the standard surgical procedure for the treatment of ulcerative colitis and familial polyposis of the colon. Nevertheless, its use in Crohn's disease patients remains controversial. A review was carried out in order to determine the present scientific evidence on the usefulness of ileal pouch-anal anastomosis in Crohn's disease patients. There are no clinical trials analysing this issue. Scientific evidence is based on case series and retrospective studies. Most authors agree that Crohn's disease remains a contraindication for ileal pouch-anal anastomosis, due to the high rate of complications and pouch failure. Nevertheless, a small group of authors consider ileal pouch-anal anastomosis as a good alternative for selected Crohn's disease patients. Both groups agree that if the pouch can be preserved, functional results are good. According to our review, current scientific evidence does not recommend ileal pouch-anal anastomosis for Crohn's disease patients.
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