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| http://dx.doi.org/10.1159/000203118 | DOI Listing |
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Dietary Profile of Women With Chronic Muscle Temporomandibular Disorder: An Observational Study.
J Oral Rehabil
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Department of Restorative Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.
Background: Temporomandibular disorder (TMD) is the main chronic pain that affects the face, and it is associated with dietary changes due to pain and dysfunction. However, there is a scarcity of studies on its impact on nutrition and vice versa.
Objectives: To assess and compare the intake of energy and nutrients among chronic TMD myalgia and asymptomatic women and to evaluate data according to dietary reference intakes (DRI) and the World Health Organization (WHO) values.
Nose-to-brain delivery of DHA-loaded nanoemulsions: A promising approach against Alzheimer's disease.
Int J Pharm
January 2025
MMDN, University of Montpellier, EPHE, INSERM, Montpellier, France; LipSTIC LabEx (ANR-11-LABX0021), Dijon, France. Electronic address:
Reduced docosahexaenoic acid (DHA) concentrations seem to be associated with an increased risk of Alzheimer's disease (AD), and DHA accretion to the brain across the blood-brain-barrier (BBB) can be modulated by various factors. Therefore, there is an urgent need to identify an efficient and non-invasive method to ensure brain DHA enrichment. In the present study, a safe and stable DHA-enriched nanoemulsion, designed to protect DHA against oxidation, was designed and administered intranasally in a transgenic mouse model of AD, the J20 mice.
View Article and Find Full Text PDFDeterminants of Maternal and Infant Omega-3 Status at 3 Months Postpartum: Findings from the APrON Longitudinal Cohort Study.
Am J Clin Nutr
January 2025
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada. Electronic address:
Background: Omega-3 long chain polyunsaturated fatty acids (LCPUFAs) are important dietary components for maternal and infant health during pregnancy and lactation.
Objective: This study investigated determinants of maternal and infant LCPUFAs status at three months postpartum and the relationship between maternal serum, mother's milk, and infant LCPUFAs.
Methods: This cross-sectional study included mothers (n=1481) and their offspring (n=526) at three months postpartum from the APrON cohort.
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Department of Psychiatry and Psychotherapy, Medical Faculty, University of Cologne, Cologne, Germany.
Background: Alzheimer's disease (AD) is the most common etiology of dementia. As the progression of the disease may be slowed down by disease-modifying therapies, but not stopped, research identifying further therapeutic approaches is necessary. Due to the multifactorial etiology of AD, targeting modifiable risk factors for dementia, including diet, is a starting point for preventive interventions.
View Article and Find Full Text PDFBackground: Oxylipins are oxygenated fatty acid (FA) metabolites that are important mediators of inflammation. Neuroinflammation is a hallmark of Alzheimer's disease (AD), and brains of AD patients contain more pro-inflammatory and less anti-inflammatory oxylipins compared to healthy controls. Free fatty acid receptor 4 (Ffar4) is a G-protein coupled receptor for medium and long-chain FAs, including, but not limited to, omega-3-polyunsaturated FAs.
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