Objective: To compare clinical features, visual characteristics, and treatment of idiopathic intracranial hypertension patients with and without papilledema.
Background: Idiopathic intracranial hypertension does not often occur without papilledema. This study estimates the prevalence and compares the clinical characteristics of idiopathic intracranial hypertension patients with and without papilledema.
Methods: We performed a cross-sectional analysis of all idiopathic intracranial hypertension patients diagnosed at the University of Utah Neuro-Ophthalmology Unit between 1990 and 2003. Patient records were reviewed for presence of papilledema and other signs, symptoms, and treatment characteristics. Each patient without papilledema was matched to the patient with papilledema who was closest to his/her age and sex. McNemar's and Wilcoxon-signed rank sum tests were used to compare characteristics between matched pairs.
Results: Among all patients (n = 353), the prevalence of those without papilledema was 5.7% (n = 20). Patients without papilledema reported photopsias (20%), and were found to have spontaneous venous pulsations (75%) and non-physiologic visual field constriction (20%) more often than did those with papilledema. Mean opening pressure, although above normal, was lower in patients without papilledema (mean = 309 mm cerebrospinal fluid) compared with those with papilledema (mean = 373 mm cerebrospinal fluid, P = .031). Idiopathic intracranial hypertension patients without papilledema had more frequent diagnostic lumbar punctures than did patients with papilledema. Visual acuities and treatment were similar between groups.
Conclusions: The clinical presentation of idiopathic intracranial hypertension without papilledema is only somewhat different from that of idiopathic intracranial hypertension with papilledema. The lower opening pressure in patients without papilledema may explain variations in symptoms and signs between the 2 groups. When there are visual field changes in idiopathic intracranial hypertension without papilledema, non-physiologic visual loss should be considered.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326261 | PMC |
| http://dx.doi.org/10.1111/j.1526-4610.2008.01324.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Radius-Maumenee syndrome (idiopathic dilated episcleral vessels).
GMS Ophthalmol Cases
December 2024
Universidade Federal do Paraná (UFPR), Curitiba, Brazil.
Purpose: Idiopathic elevated episcleral venous pressure (IEEVP) or Radius-Maumenee syndrome (RMS) is a rare disease without any identified underlying cause. An increasing episcleral venous pressure (EVP) leads to raised intraocular pressure (IOP) and consequently glaucomatous damage of the optic nerve. The objective of this paper is to report this rare condition as well as its clinical management.
View Article and Find Full Text PDFOptic nerve sonographic parameters in idiopathic intracranial hypertension, case-control study.
Sci Rep
January 2025
Assistant Professor of Neurology, Department of Neurology, Tanta University, Tanta, Egypt.
The most common diagnostic error of IIH is inaccurate funduscopic examination. Moreover, IIH could be diagnosed without papilledema. Trans orbital sonography could be used as a non-invasive and cheap tool for discovering increased ICP (intracranial Pressure).
View Article and Find Full Text PDFIdiopathic Intracranial Hypertension: Pre- and Post-treatment Radiologic Analyses.
Cureus
December 2024
Radiology, JCC Diagnostic Imaging, Viana do Castelo, PRT.
We discuss a case of a 19-year-old female who presented with pressure headaches and progressive vision loss. In the emergency department, a series of diagnostic tests were conducted, including CT, MRI, and lumbar puncture with measurement of opening pressure. All these examinations yielded results consistent with the suspected diagnosis of idiopathic intracranial hypertension (IIH).
View Article and Find Full Text PDFIdiopathic intracranial hypertension: Imaging and clinical fundamentals.
World J Radiol
December 2024
Research Unit of Radiology and Medical Imaging, School of Medicine, National and Kapodistrian University of Athens, Athens 11528, Greece.
Neuroimaging is a paramount element for the diagnosis of idiopathic intracranial hypertension, a condition characterized by signs and symptoms of raised intracranial pressure without the identification of a mass or hydrocephalus being recognized. The primary purpose of this review is to deliver an overview of the spectrum and the specific role of the various imaging findings associated with the condition while providing imaging examples and educational concepts. Clinical perspectives and insights into the disease, including treatment options, will also be discussed.
View Article and Find Full Text PDFDecreased Choroidal Vascular Index in Idiopathic Intracranial Hypertension.
Brain Behav
January 2025
Department of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Introduction: We aimed to explore the difference in choroidal vascular parameters using swept-source optical coherence tomography (SS-OCT) in patients with idiopathic intracranial hypertension (IIH) compared to controls. We also explored the ability of the choroidal parameters to reflect elevated intracranial pressure (ICP) in patients with IIH.
Methods: This observational study recruited patients diagnosed with IIH and healthy controls.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!