Indium summer: The use of low-valent indium species in organic chemistry was, until quite recently, underdeveloped. Then came reports of indium(I) halides serving as excellent catalysts for the allylation of ketones and N-acylhydrazones with pinacol allylboronates, and more recently of indium(0) being used as a catalyst for the allylation of ketones in water.
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http://dx.doi.org/10.1002/cssc.200800243 | DOI Listing |
Front Chem
December 2024
Department of Chemistry, University of Lucknow, Lucknow, India.
Rhodium(III) catalysis has been used for C-H activation of -nitrosoanilines with substituted allyl alcohols. This method provides an efficient synthesis of the functional -nitroso β-aryl aldehydes and ketones with low catalyst loading, high functional group tolerance, and superior reactivity of allyl alcohols toward -nitrosoanilines. We demonstrated that reaction also proceeds through the one-pot synthesis of -nitrosoaniline, followed by subsequent, C-H activation.
View Article and Find Full Text PDFEur J Med Chem
December 2024
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, bld. 1, Moscow, 119334, Russia. Electronic address:
Thevinols and their 3-O-demethylated relatives, orvinols, are derivatives of the Diels-Alder adduct of natural alkaloid thebaine with methyl vinyl ketone. Taken together, thevinols and orvinols constitute an important family of opioid receptor (OR) ligands playing an important role in both the OR mediated antinociception and OR antagonism. Herein, we disclose for the first time the antagonist activity of the N-allyl substituted orvinol derivative fluorinated within the pharmacophore associated with C(20) and its surrounding.
View Article and Find Full Text PDFChem Rec
December 2024
Department of Pharmacy, The Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
The catalytic asymmetric allylation reaction involving allylboron species has emerged as a powerful tool to access highly stereoselective allylation products. In the early years, most of the researches focused on the reaction of unsubstituted allylboronates with ketones or imines. With the synthesis of complex substituted allylboronates, allylboronic acids and allyltrifluoroborates, the type of reactions and the variety of substrates are greatly expanded.
View Article and Find Full Text PDFPolymers (Basel)
November 2024
Institute of Inorganic and Analytic Chemistry, Clausthal University of Technology, 38678 Clausthal-Zellerfeld, Germany.
Polyurethane (PUR) soft foams release malodorous and potentially toxic compounds when exposed to oxidative conditions. Current chamber test methods cannot distinguish between pre-existing volatiles and those formed during oxidation, nor can they assess the formation rates of oxidation products. We subjected PUR soft foam to oxidative treatment in a continuous air flow at 120 °C.
View Article and Find Full Text PDFMolecules
November 2024
School of Chemistry, Northeast Normal University, Changchun 130024, China.
The traditional liquid electrolytes pose safety hazards primarily attributed to the flammability of organic solvent, whereas solid-state electrolytes can significantly enhance the safety of lithium-ion batteries. Polymer solid electrolytes are being considered as an effective solution due to their excellent flexibility and low cost, but they suffer low ionic conductivity or high interface impedance. Here, the ketone-containing allyl acetoacetate monomers were polymerized within the cellulose membrane via UV photopolymerization to prepare a cellulose-supported poly-allyl acetoacetate polymer electrolyte.
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