Acute mountain sickness (AMS) is usually seen in unacclimatized individuals ascending to a high altitude within a short period of time. Severe cases may be complicated with multiorgan dysfunction syndrome (MODS), which results in very high mortality. We reported a case of a 20-year-old girl who developed AMS complicated with high altitude pulmonary edema (HAPE), high altitude cerebral edema (HACE), and acute renal failure. Continuous renal replacement therapy (CRRT) was successfully carried out in this patient and achieved satisfactory effects. The treatment of this patient suggests that early intervention of CRRT may be a useful therapy for patient with severe AMS, especially those with MODS.
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