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External auditory canal metastasis revealing bronchogenic carcinoma: A case report and literature review.
SAGE Open Med Case Rep
May 2024
ENT Department and Research Laboratory LR23ES01, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Article Synopsis
- The report details a rare case of bronchogenic adenocarcinoma that initially spread to the external auditory canal in a 64-year-old man with a history of bladder cancer.
- The patient presented with persistent right ear infection symptoms, and imaging showed a mass obstructing the right ear canal and invading the middle ear.
- Further tests revealed extensive lung involvement with metastasis to the brain, and the patient received local radiation therapy and chemotherapy after being staged as T4N2M1c.
A 63-year-old man was admitted to a hospital owing to shortness of breath. He was diagnosed as having gastric cancer with pulmonary carcinomatous lymphangitis(PCL)and disseminated carcinomatosis of the bone marrow(DCBM). Regarding tumor markers, carcinoembryonic antigen(CEA)and carbohydrate antigen 19-9(CA19-9)levels increased to 332 ng/ mL and 921 U/mL, respectively.
View Article and Find Full Text PDFPrognostic Impact of Visceral Pleural Invasion in Resected Solitary Lung Metastases from Gastric Cancer.
Ann Thorac Cardiovasc Surg
December 2023
Division of Thoracic Surgery, Saiseikai Utsunomiya Hospital, Utsunomiya, Tochigi, Japan.
Purpose: Pulmonary resection of metastases from gastric cancer is extremely rare because gastric cancer metastasis to the lungs or thoracic cavity occurs as multiple pulmonary metastases, carcinomatous lymphangitis, or carcinomatous pleurisy. Therefore, the significance of surgery for pulmonary metastasis of gastric cancer remains unclear. This study aimed to investigate the surgical outcomes and prognostic factors for survival after the resection of pulmonary metastases from gastric cancer.
View Article and Find Full Text PDFLong-term treatment with inhibitors for postoperative recurrence of ALK-rearranged lung cancer.
Int Cancer Conf J
October 2022
Department of Surgery, Kishima Main Hospital, 3-33 Rakuonji, Yao City, Osaka 581-0853 Japan.
We encountered a 40-year-old female patient who developed, in chronological order, carcinomatous pleuritis and lymphangitis, multiple lymph node metastases, brain metastases, and intramedullary spinal cord metastases after resection of lung adenocarcinoma followed by adjuvant chemotherapy. Echinoderm microtubule-associated protein-like 4 (EML4) and the anaplastic lymphoma kinase (ALK) fusion gene, variant 2 was identified in her cancer cells. By changing the ALK inhibitors from the 1st to 3rd generation each time when metastases were identified and incorporating local treatments in a timely fashion, such as metastasectomy or radiation therapy, she has survived for more than 11 years since the start of treatment, while maintaining a good Eastern Cooperative Oncology Group Performance Status (ECOG-PS) score of 0.
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