[GPs' perceptions of the Institute for Rational Pharmacotherapy].

Ugeskr Laeger

Center for Anvendt Sundhedstjenesteforskning og Teknologivurdering, Syddansk Universitet, DK-5000 Odense C.

Published: February 2009

Introduction: A questionnaire study was conducted among Danish general practitioners (GPs) as part of an international evaluation of the Institute for Rational Pharmacotherapy (IRF). The aim was to investigate GPs' use and opinion of the IRF's activities.

Material And Methods: A questionnaire was sent to a random sample of 500 GPs, who were asked about their level of knowledge and frequency of use of IRF's activities, as well as their opinion on the relevance, credibility and independence of the IRF's activities.

Results: The response rate was 59%. IRF is generally not the first source of information about new drugs, but is frequently used in the search for information about comparability between drugs and in relation to sudden drug warnings. IRF's Rational Pharmacotherapy bulletin and its GP courses, which nine out of ten GPs knew about, were considered to be highly relevant by 80% and 71%, respectively. All of IRF's activities were considered highly credible. Most GPs felt that the IRF's information increased their confidence in prescribing decisions (84%) and supported them in their role as a GP (88%).

Conclusion: IRF's activities support the GP's prescribing role through the production of credible, neutral and evidence-based pharmacotherapeutic information that is not available elsewhere. IRF could further refine its dissemination methods, however, in order to reach more GPs and to increase the use of its information.

Download full-text PDF

Source

Publication Analysis

Top Keywords

irf's activities
12
institute rational
8
rational pharmacotherapy
8
considered highly
8
irf's
7
gps
5
[gps' perceptions
4
perceptions institute
4
rational pharmacotherapy]
4
pharmacotherapy] introduction
4

Similar Publications

Potential therapeutic targets for inflammation in toll-like receptor 4 (TLR4)-mediated signaling pathways.

Int Immunopharmacol

November 2016

Center for Biosciences and Biomedical Engineering (BSBE), Indian Institute of Technology (IIT), Indore, MP, India. Electronic address:

Inflammation is set off when innate immune cells detect infection or tissue injury. Tight control of the severity, duration, and location of inflammation is an absolute requirement for an appropriate balance between clearance of injured tissue and pathogens versus damage to host cells. Impeding the risk associated with the imbalance in the inflammatory response requires precise identification of potential therapeutic targets involved in provoking the inflammation.

View Article and Find Full Text PDF

Background: The Interferon Regulatory Factors (IRFs) are transcription factors involved in immune responses and oncogenesis and most of them are classified as tumour suppressors. The expression and activation of IRF(s) are stimulated by several cytokines and by DNA damage. Here we examine the role of the IRF-1 in the response of ovarian cancer cells to the front-line chemotherapeutic drug cisplatin (CDDP).

View Article and Find Full Text PDF

Interferon regulatory factors (IRFs) repress transcription of the chicken ovalbumin gene.

Gene

June 2009

Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN, USA.

Although the ovalbumin (Ov) gene has served as a model to study tissue-specific, steroid hormone-induced gene expression in vertebrates for decades, the mechanisms responsible for regulating this gene remain elusive. Ov is repressed in non-oviduct tissue and in estrogen-deprived oviduct by a strong repressor site located from -130 to -100 and designated CAR for COUP-TF adjacent repressor. The goal of this study was to identify the CAR binding protein(s).

View Article and Find Full Text PDF

[GPs' perceptions of the Institute for Rational Pharmacotherapy].

Ugeskr Laeger

February 2009

Center for Anvendt Sundhedstjenesteforskning og Teknologivurdering, Syddansk Universitet, DK-5000 Odense C.

Introduction: A questionnaire study was conducted among Danish general practitioners (GPs) as part of an international evaluation of the Institute for Rational Pharmacotherapy (IRF). The aim was to investigate GPs' use and opinion of the IRF's activities.

Material And Methods: A questionnaire was sent to a random sample of 500 GPs, who were asked about their level of knowledge and frequency of use of IRF's activities, as well as their opinion on the relevance, credibility and independence of the IRF's activities.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!