Background: Oxygen uptake efficiency slope (OUES) is proposed as an objective index of cardiorespiratory functional reserve. The AIM of the present study was to evaluate the effect of coexisting respiratory diseases on OUES in patients with chronic heart failure (CHF) (New York Heart Association class II-III) during incremental exercise testing.
Patients And Methods: Fifty-five males were allocated to three groups: group 1-19 patients with only CHF (CHF); group 2-17 patients with CHF and a history of respiratory disease (CHF-RD); group 3-19 matched controls (C). They all underwent comprehensive lung function testing and symptom-limited ramp cardiopulmonary exercise test on a cycle ergometer.
Results: The patients with a history of respiratory diseases had the lowest value of OUES, but their results were not significantly different from those of the CHF patients (OUES mL.min(-1).logL(-1)= 1461 +/- 268 vs. 1571 +/- 383 vs. 2112 +/- 263 in controls). Significant correlation was found between OUES and important functional variables: VO2peak (r=0.833), V(E)/NCO2 slope (r = -0.757), FEV1 (r=0.582), T(L,CO) (r=0.574), and EF% (r=0.350).
Conclusions: OUES is significantly reduced in patients with CHF and tends to be lower in the presence of a respiratory disease. It can be regarded as an useful, reliable physiologic marker of reduced ventilatory efficiency and cardiorespiratory reserve in chronic heart failure.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
BTKi-induced cardiovascular toxicity in CLL: Risk mitigation and management strategies.
Blood Rev
January 2025
Clinic of Hematology, University Clinical Centre of Serbia, Serbia; Faculty of Medicine, University of Belgrade, Serbia. Electronic address:
Targeted therapies, consisting of Bruton tyrosine kinase inhibitors (BTKis) or BCL-2 inhibitors, are the mainstay of contemporary treatments for chronic lymphocytic leukemia (CLL). The most common adverse effects (AEs) of BTKis are fatigue, bruising, infection, hematological and cardiovascular AEs. While AEs during treatment are usually mild (grades 1 and 2), grade 3 and 4 AEs have been detected in some patients, necessitating additional medical care and temporary or permanent drug discontinuation.
View Article and Find Full Text PDFRisk trajectory of cardiovascular events after an exacerbation of chronic obstructive pulmonary disease: A systematic review and meta-analysis.
Eur J Intern Med
January 2025
Internal Medicine and Stroke Care ward, Department of Promoting Health, Maternal-Infant. Excellence and Internal and Specialized Medicine (Promise) G. D'Alessandro, University of Palermo, Palermo Italy.
Background: Exacerbations of chronic obstructive pulmonary disease (COPD) are known to increase the risk of cardiovascular (CV) events and mortality. However, the temporal trend of this risk has not fully elucidated. This systematic review and meta-analysis aims to quantify the risk of CV events after COPD exacerbations over different time periods.
View Article and Find Full Text PDFCardiovascular risk assessment: Missing albuminuria contributing to gender inequality.
Nefrologia (Engl Ed)
January 2025
Division of Nephrology IIS-Fundacion Jimenez Diaz, Department of Medicine, Universidad Autónoma de Madrid, Madrid, Spain; RICORS2040, Carlos III Institute of Health, Madrid, Spain.
Introduction: Chronic kidney disease (CKD) is associated with high cardiovascular disease (CVD) risk, and requires specific interventions to decreases CVD risk. The guidelines indicate that systematic global CVD risk assessment is recommended in individuals with any major vascular risk factor. The European Society Cardiology (ESC) guidelines, he European Renal Association (ERA) Council and the Spanish Society of Nephrology (S.
View Article and Find Full Text PDFAssessment of Online YouTube Videos as a Source of Information and Instruction for Pulmonary Rehabilitation.
Respir Med
January 2025
Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada; Division of Respirology, Temerty Faculty of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada. Electronic address:
Background/objectives: Pulmonary rehabilitation (PR) benefits individuals with chronic respiratory conditions beyond COPD; however, the quality of online resources has not been evaluated. The aims of this study were to assess the content, quality, and comprehensibility of YouTube videos that provide PR to individuals with chronic lung diseases other than COPD.
Methods: A search was conducted on YouTube for videos related to PR on non-COPD conditions, with the first 350 videos screened for eligibility (2004-2024).
Prognostic values of proteinuria in patients with acute heart failure.
J Cardiol
January 2025
Department of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan; Japan Agency for Medical Research and Development-Core Research for Evolutionary Medical Science and Technology (AMED-CREST), Japan Agency for Medical Research and Development, Tokyo, Japan.
Background: Renal dysfunction is significantly associated with poor prognosis in patients with heart failure. However, the prognostic significance of proteinuria as a potential marker of an impaired glomerular filtration barrier in acute heart failure (AHF) remains unclear. We aimed to investigate the prognostic value of urinary protein/creatinine ratio (PCR) in patients with AHF.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!