Aim: The commonest benign lytic bone disorders, which compromise the bone robustness include juvenile bone cysts. Provided the cysts do not undergo spontaneous healing, which is commonly facilitated by pathological fracturing or introduction of osteosynthetic material into the cyst, the cystic cavity must be filled in. Numbers of potential defect management procedures, including use of corticoids, autografts, allografts or recently introduced methods of application of synthetic anorganic biomaterials, have been used. The aim of this study is to assess a possibility of the biomaterials use in the management of benign cysts in children.
Material And Methodology: The study included 20 juvenile bone cysts patients aged 10-17, treated with tricalcium phosphate during 2004-2007 in the KDCHOT. The authors assessed rates of the procedures, therefore a number of required hospitalizations and total anesthesias, intraoperative complications, postoperative complications, durations of hospitalization and treatment outcomes, based on Neer criteria, including the cyst's time-to-heal interval. In addition, evaluation of the results was related to the cyst's location.
Results: The treatment results, assessed according to the Neer criteria, show that 90% of the cysts healed and did not require further surgical intervention. Poor outcome was recorded in 2 subjects, who required further surgery due to skeletal instability. Intraoperative and perioperative complications were insignificant, the average duration of hospitalization was 4 days and the average time-to-heal period following primary or secondary percutanneous cyst filling was 15 months (ranging from 13 to 20 months).
Conclusion: The studied method of the tricalcium phosphate application resulted in reduced rates of surgical procedures required for the defect healing. Furthermore, it is not associated with serious perioperative or intraoperative complications and the hospitalization duration may be very short.
Download full-text PDF |
Source |
---|
Diagn Pathol
January 2025
Cell Culture Laboratory, School of Dentistry, Federal University of Para, Rua Augusto Correa, 01 Guama, Belem, PA, 66075110, Brazil.
Background: Considering the significant participation of the microenvironment in the local aggressiveness of odontogenic keratocysts, this study aims to evaluate the expression of ADAMTS-1 and its substrates, versican, aggrecan and brevican in this locally invasive odontogenic cyst.
Methods: Immunohistochemistry and polymerase chain reaction (PCR) were conducted on 30 cases of odontogenic keratocysts (OKCs) and 20 dental follicles (DFs).
Results: The immunohistochemical expression of these proteins was predominantly cytoplasmic and granular across all samples.
J Shoulder Elbow Surg
December 2024
Bone and Joint Reconstruction Research Center, Department of Orthopedics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Background: Many unicameral bone cysts (UBC) can be resolved or treated conservatively. Managing persistent symptomatic UBCs in the humerus is particularly challenging. An effective surgical method with low complications is significant for treatment.
View Article and Find Full Text PDFAm J Sports Med
January 2025
University of Alabama at Birmingham, Birmingham, Alabama, USA.
Background: Benign bone lesions are a common incidental finding in athletes during workup for musculoskeletal complaints, and athletes are frequently advised to halt participation in contact sports. There are no current guidelines to assist clinicians in referring patients with these lesions to a subspecialist or in advising athletes on the safety of returning to sport.
Purpose: To assist sports medicine physicians in appropriate referral for patients with benign bone lesions through presentation of a literature review and the case of an adolescent athlete with a benign bone lesion in a location with a significant fracture risk.
Arch Bone Jt Surg
January 2024
Division of Shoulder and Elbow Surgery, Rothman Orthopaedic Institute, Philadelphia, PA, USA.
Posterior shoulder instability (PSI) is a shoulder pathology that is challenging to diagnose, leading to treatment delay and exacerbation of symptoms. Etiology can be both traumatic and atraumatic, and a comprehensive clinical history plays a significant role in achieving diagnosis. Imaging in the setting of PSI can reveal a reverse-Bankart lesion, a reverse Hill-Sachs lesion, posterior labral cysts, and potentially glenoid or lesser tuberosity fractures.
View Article and Find Full Text PDFJ Med Case Rep
December 2024
Department of Gastroenterology, Shahid Mohammadi Hospital, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Background: Systemic lupus erythematosus is a multi-organ autoimmune disorder that is treated by immunosuppressive agents that weaken the immune defense against opportunistic pathogens and latent infections such as strongyloidiasis. Herein, we report the case of a 43-year-old woman known to have systemic lupus erythematosus who presented with gastrointestinal symptoms, edema, and bone pain 2 months after receiving immunosuppressive treatment.
Case Presentation: A 43-year-old Iranian female known to have systemic lupus erythematosus and antiphospholipid syndrome presented with abdominal pain, nausea, vomiting, and generalized edema.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!