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Lansoprazole-induced acute pancreatitis.
Turk J Gastroenterol
October 2014
Department of Gastroenterology, Başkent University Faculty of Medicine, Ankara, Turkey.
Lansoprazole-induced acute lung and liver injury: a case report.
Int J Clin Pharmacol Ther
December 2014
A 61-year old woman was admitted with increasing dyspnea and deranged liver function tests. A chest X-ray revealed small volume lungs with reticulo-nodular shadowing. High resolution computed tomography of the chest revealed interlobular septal thickening.
View Article and Find Full Text PDFLansoprazole-induced acute allergic interstitial nephritis in a renal transplant recipient: a case report.
Int Urol Nephrol
December 2012
Department of Nephrology, Hacettepe University, Ankara, Turkey.
Drug-induced interstitial nephritis is one of the causes of graft dysfunction in renal transplant recipients. Although commonly implicated as a cause of drug-induced interstitial nephritis in the general population, proton pump inhibitor-induced interstitial nephritis has not yet been reported in renal transplant recipients. Trimethoprim-sulfamethoxazole is responsible for most cases of interstitial nephritis in this population.
View Article and Find Full Text PDFAttenuation of stress-induced gastric lesions by lansoprazole, PD-136450 and ranitidine in rats.
Mol Cell Biochem
March 2011
Department of Pharmacology, Faculty of Medicine & Health Sciences, UAE University, Al Ain, United Arab Emirates.
Combining restraint with cold temperature (4°C) consistently induces gastric ulceration in rats after 3.5 h. The cold restraint-stress (CRS) method provides a suitable model for acute ulcer investigations.
View Article and Find Full Text PDFThe expression of heme oxygenase-1 induced by lansoprazole.
J Clin Biochem Nutr
July 2009
Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Our previous studies have demonstrated that lansoprazole inhibits acute inflammatory reactions as well as intestinal mucosal injuries induced by ischemia-reperfusion or indomethacin administration in rats. Thus, proton pump inhibitors such as lansoprazole have been demonstrated to prevent gastrointestinal mucosal injury by mechanisms independent of acid inhibition. In our in vitro study, lansoprazole induced the expression of heme oxygenase-1 (HO-1) on rat gastric epithelial cells (RGM-1 cells), and exerted anti-inflammatory effect on the dependent of HO-1 expression.
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