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Could Nocturnal Chronic Hypoxia Cause Ocular Surface Symptoms by Affecting Limbal Epithelial Cells in Patients With Obstructive Sleep Apnea?
Cornea
January 2025
Department of Pulmonology, Trakya University Faculty of Medicine, Edirne, Turkey; and.
Purpose: To investigate the effect of nocturnal chronic hypoxia on the thickness changes of the corneal limbal epithelial area that provides regeneration of the corneal epithelium and ocular surface evaluation parameters in patients with obstructive sleep apnea (OSA).
Methods: All patients diagnosed with OSA and the control group underwent a complete ophthalmological examination, including slit-lamp examination and funduscopy. Tear break-up time, Schirmer test-I, Ocular Surface Disease Index Questionnaire, and anterior segment optical coherence tomography were performed with fluorescein sterile strip for ocular surface evaluation.
An assessment of bacterial transmission via rebound tonometry: An pilot study.
Open Vet J
November 2024
Perth Animal Eye Hospital, Manning, Perth, Western Australia.
Background: Bacterial contamination of medical equipment is a significant risk in both human and veterinary medicine, leading to potential cross-contamination between clinicians, technicians, patients, and healthcare professionals. Pathogens can persist on surfaces, resulting in healthcare-associated infections. Tonometry used to measure intraocular pressure for diagnosing conditions like glaucoma and uveitis, is crucial in both human and veterinary care.
View Article and Find Full Text PDFCorneal cross-linking.
Prog Retin Eye Res
January 2025
ELZA Institute, Webereistrasse 2, CH-8953, Dietikon, Switzerland; Laboratory for Ocular Cell Biology, University of Zurich, Winterthurerstrasse 190, CH-8057, Zurich, Switzerland; Faculty of Medicine, University of Geneva, Rue Michel-Servet 1, CH-1206, Geneva, Switzerland. Electronic address:
First introduced over 20 years ago as a treatment for progressive keratoconus, the original "Dresden" corneal cross-linking (CXL) protocol involved riboflavin saturation of the stroma, followed by 30 min of 3 mW/cm-intensity ultraviolet-A (UV-A) irradiation. This procedure generates reactive oxygen species (ROS) that cross-link stromal molecules, thereby stiffening the cornea and counteracting the ectasia-induced weakening. Due to their large size, riboflavin molecules cannot readily pass through the corneal epithelial cell tight junctions; thus, epithelial debridement was performed.
View Article and Find Full Text PDFLetter Regarding: Clinical Outcomes and Indications of In-Office Sutureless Dried Gamma Ray-Sterilized Human Amniotic Membrane Transplantation With Bandage Contact Lenses in Various Ocular Surface Disorders.
Cornea
December 2024
Department of Ophthalmology, All India Institute of Medical Sciences, Kalyani, West Bengal, India.
Outcomes of pediatric sterile keratitis posthypotonic collagen cross-linking.
Oman J Ophthalmol
October 2024
Cornea and Anterior Segment, Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Vijayawada, Andhra Pradesh, India.
In this case series, we will describe sterile keratitis in the early postoperative period after hypotonic collagen cross-linking (CXL) in two pediatric cases. This is a retrospective case series of two eyes of two children who developed inflammatory keratitis with central corneal haze after uneventful epithelial-off hypotonic CXL. After ensuring microbiological sterility, appropriate treatment with topical steroids and lubricants was started.
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