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Predictive modeling to evaluate long-term treatment effectiveness of darvadstrocel in patients with complex perianal fistulas in Crohn's disease.
BMC Gastroenterol
December 2024
Formerly Gastroenterology Department, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Hospital Clínic de Barcelona, Barcelona, Spain.
Background: Current therapies for complex Crohn's perianal fistulas (CPF) have a limited ability to achieve long-term healing. Darvadstrocel (DVS) is an expanded allogeneic adipose-derived mesenchymal stem cell therapy that has demonstrated efficacy in treating complex CPF in clinical trials. There are, however, limited long-term comparative data with standard of care (SoC).
View Article and Find Full Text PDFA blended mindfulness-based stress reduction program to improve diabetes self-management among people with type 2 diabetes mellitus: a mediation effect analysis.
Ann Behav Med
December 2024
Xiangya School of Nursing, Central South University, Changsha, Hunan Province, China.
Article Synopsis
- * One hundred participants were divided into two groups to compare the effects of blended MBSR with standard care, showing significant improvements in the MBSR group over a 12-week period.
- * The findings suggest that reductions in perceived stress and anxiety are key factors that improve diabetes self-efficacy, which in turn enhances diabetes self-management, while depressive symptoms did not play a mediating role.
Bioactive Phyto-Compounds with Antimicrobial Effects and AI: Results of a Desk Research Study.
Microorganisms
May 2024
Department of Social Medicine and Health Care Organisation, Faculty of Public Health, Medical University of Varna, 9002 Varna, Bulgaria.
Resistance of microorganisms to antibiotics represents a formidable global challenge, manifesting in intricate public health ramifications including escalated mortality rates and augmented healthcare costs. The current efforts to manage antimicrobial resistance (AMR) are limited mainly to the standard therapeutic approaches. The aim of this study is to present and analyze the role of artificial intelligence (AI) in the search for new phyto-compounds and novel interactions with antimicrobial effects.
View Article and Find Full Text PDFSurvival trends and patient characteristics between 2004 and 2016 for breast cancer in Japan based on the National Clinical Database-Breast Cancer Registry.
Breast Cancer
March 2024
Department of Medical Oncology, Fukushima Medical University, Fukushima, Japan.
This is a prognostic report by the Japanese Breast Cancer Society on breast cancer extracted from the National Clinical Database-Breast Cancer Registry of Japan. Here, we present a summary of 457,878 breast cancer cases registered between 2004 and 2016. The median follow-up duration was 5.
View Article and Find Full Text PDFPreface to the 9th Biennial COAST Conference: Harnessing Technology and Biomedicine for Personalized Orthodontics.
Orthod Craniofac Res
December 2023
UCLA School of Dentistry, Los Angeles, California, USA.
Objective: The Consortium on Orthodontic Advances in Science and Technology (COAST) convened for its 9th biennial conference titled 'Harnessing Technology and Biomedicine for Personalized Orthodontics' to explore cutting-edge craniofacial research towards building the foundations for precision care in orthodontics.
Setting And Sample Population: Seventy-five faculty, scholars, private practitioners, industry, residents and students met at the UCLA Arrowhead Lodge on 6-9 November 2022 for networking, scientific presentations and facilitated discussions. Thirty-three speakers provided state-of-the-art, evidence-based scientific and perspective updates in craniofacial and orthodontic-related fields.
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