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Background: There is continuous demand for safe, effective cosmetic ingredients to treat the signs of aging skin, including fine lines, wrinkles, brown spots, discoloration, laxity, and sagging. While there are a plethora of cosmeceutical peptides, few combine anti-aging and anti-inflammatory benefits with small size.
Methods: Preclinical and clinical studies evaluated the anti-inflammatory properties, anti-aging benefits, and tolerability of acetyl dipeptide-31 amide (AP31), a novel, small, anti-aging micropeptide, to understand its impact as a multifaceted, cosmetic, anti-aging, and anti-inflammaging ingredient.
Aesthetic Reconstruction of Huge Full-Thickness Defection of Lower Eyelid Using Nasolabial Mucosal-Myocutaneous Propeller Flap.
J Craniofac Surg
January 2025
Department of Plastic Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Reconstruction after the excision of a lower eyelid tumor should be focused on the restoration of both functionality and aesthetic appeal. Accurate identification and appropriate intervention are crucial for the favorable resolution of the condition. This technique used a nasolabial mucosal-myocutaneous propeller flap to reconstruct a huge full-thickness defection of right lower eyelid because of basal cell carcinoma.
View Article and Find Full Text PDFThe Comparison Competence Nasolabial and Forehead Flap for Reparation Nasal Tissue Defect of Basal Cell Carcinoma.
J Maxillofac Oral Surg
December 2024
Department of Surgery, Loqman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: Both nasolabial and forehead flaps are utilized for the reparation of nasal soft tissue defects that result from basal cell carcinoma. Utilizing the forehead flap needs twice operation for scar correction and flap base amputation while the nasolabial flap is a more effective one-stage technique.
Material And Methods: This prospective study was performed on patients with BCC involving nasal tip and ala regions based on the results of the initial biopsy and was admitted to the surgery department of the Loghman-Hakim Hospital to resect the lesion.
Molluscum contagiosum (MC) virus is a poxvirus that infects epidermal keratinocytes producing cutaneous nodules with characteristic intracytoplasmic inclusions. Intradermal nevus is a benign lesion that typically presents as clusters of melanocytes within the dermal layer of skin. Although both MC and melanocytic nevus are common lesions, MC arising within a melanocytic nevus is a rare event with only a few cases published in the literature.
View Article and Find Full Text PDFCase report: Multiple facial trichoepitheliomas caused by p.Val835SerfsTer52 variant of gene.
Front Med (Lausanne)
September 2024
Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russia.
Article Synopsis
- Brooke-Spiegler syndrome (BSS) is an autosomal dominant condition linked to a gene mutation, leading to the formation of multiple benign skin tumors known as trichoepitheliomas.
- A case study reveals a young female with a previously unknown mutation (c.2501dupC) causing this syndrome, which was confirmed through genetic testing involving her family.
- Despite surgical removal of some tumors using a CO laser, new lesions continued to emerge, suggesting that current treatments are inadequate and highlighting the need for future targeted therapies not currently available.
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