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Effects of Extracted Pulse Proteins on Lipid Targets for Cardiovascular Risk Reduction: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Nutrients
November 2024
Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
Background: Many clinical practice guidelines recommend dietary pulses for the prevention and management of cardiovascular disease and diabetes. The impact of extracted pulse proteins remains unclear. We therefore conducted a systematic review and meta-analysis of randomized controlled trials of the effect of extracted pulse proteins on therapeutic lipid targets.
View Article and Find Full Text PDFEffect of Soy Isoflavones on Measures of Estrogenicity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Adv Nutr
January 2025
Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada. Electronic address:
Article Synopsis
- There is a growing push for increased plant food consumption, particularly soy foods, which have potential health benefits for women, despite ongoing controversies regarding their effects.
- A systematic review and meta-analysis of 40 randomized trials involving over 3,000 postmenopausal women were conducted to assess the impacts of soy isoflavones on various estrogen-related measures.
- The results showed no significant effects of soy isoflavones on endometrial thickness, vaginal maturation, follicle-stimulating hormone, or estradiol levels, indicating that they may function as selective estrogen receptor modulators rather than acting like estrogen itself.
A Systematic Review on the Impact of Plant-Based Milk Consumption on Growth and Nutrition in Children and Adolescents.
J Nutr
November 2024
Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Canada; Department of Pediatrics, St. Michael's Hospital, Toronto, Canada; Joannah and Brian Lawson Centre for Child Nutrition, University of Toronto, Toronto, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada; Department of Paediatrics, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario. Electronic address:
Article Synopsis
- Children are increasingly drinking plant-based milks, but their effects on growth and nutrition remain uncertain.
- A systematic review analyzed studies from various databases to evaluate how plant-based milk impacts the growth and nutrition of children ages 1-18.
- Findings indicated that children consuming plant-based milk tended to have lower BMI, height, and vitamin D levels compared to those drinking cow milk, while fortified soy milk could benefit bone health in some adolescents.
The Portfolio Diet and HbA1c in Adults Living with Type 2 Diabetes Mellitus: A Patient-Level Pooled Analysis of Two Randomized Dietary Trials.
Nutrients
August 2024
Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
The Portfolio Diet, a dietary pattern of cholesterol-lowering foods, is also rich in low glycemic index (GI) foods. While strong evidence supports clinically meaningful reductions in cholesterol, evidence on the relationship between the Portfolio Diet and diabetes management is lacking. To evaluate the relationship between the Portfolio Diet and glycated hemoglobin (HbA1c) as a determinant of glycemic control among adults living with type 2 diabetes mellitus (T2DM).
View Article and Find Full Text PDFSimulation model to assess the validity of the clinical portfolio diet score used in the PortfolioDiet.app for dietary self-tracking: a secondary analysis of a randomized controlled trial in hyperlipidemic adults.
Front Nutr
August 2024
Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Introduction: The Portfolio Diet combines cholesterol-lowering plant foods for the management of cardiovascular disease risk. However, the translation of this dietary approach into clinical practice necessitates a user-friendly method for patients to autonomously monitor their adherence.
Objective: This study aimed to develop and validate the clinical-Portfolio Diet Score (c-PDS) as a food-based metric to facilitate self-tracking of the Portfolio Diet.
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