Catalytic formal Homo-Nazarov cyclization.

Org Lett

Laboratory of Catalysis and Organic Synthesis Ecole Polytechnique Fédérale de Lausanne EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne, Switzerland.

Published: February 2009

AI Article Synopsis

Article Abstract

The first catalytic method for the cyclization of vinyl-cyclopropyl ketones (formal homo-Nazarov reaction) is reported. Starting from activated cyclopropanes, heterocyclic, and carbocyclic compounds were obtained under mild conditions using Brønsted acid catalysts. Preliminary investigation of the reaction mechanism indicated a stepwise process.

Download full-text PDF

Source
http://dx.doi.org/10.1021/ol802970gDOI Listing

Publication Analysis

Top Keywords

formal homo-nazarov
8
catalytic formal
4
homo-nazarov cyclization
4
cyclization catalytic
4
catalytic method
4
method cyclization
4
cyclization vinyl-cyclopropyl
4
vinyl-cyclopropyl ketones
4
ketones formal
4
homo-nazarov reaction
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!