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Current Applications and Future Directions for Vascular Stents with Stem Cells in the Treatment of Intracranial Aneurysms: A Mini-Review.
Curr Stem Cell Res Ther
January 2025
University Radiology, Rutgers Robert Wood Johnson Medical School Department of Interventional Radiology New Jersey United States.
Vascular stents and stem cells have been used in high-acuity cases for many decades, particularly in cardiology. Providing the physician with another avenue of treatment, they have had a reasonable amount of success. However, there has been very little research conducted on seeding vascular stents with stem cells when treating intracranial aneurysms.
View Article and Find Full Text PDFImprovement of post-periodontitis-therapy inflammatory state in diabetics: a meta-analysis of randomized controlled trials.
Clin Oral Investig
September 2024
Division of Periodontics, Dental School, Federal University of Rio de Janeiro, CidadeUniversitária, 325 Prof. Rodolpho Paulo Rocco St, Rio de Janeiro, RJ, Brazil.
Article Synopsis
- The systematic review evaluated how periodontal therapy affects inflammation and oxidative stress markers in type 2 diabetes patients with periodontitis.
- Reviews of 1,062 studies identified 14 eligible trials with 1,223 participants, showing moderate-quality evidence that periodontal treatment lowers c-reactive protein levels, a marker of inflammation, particularly notable in smokers.
- The findings suggest that non-surgical periodontal therapy can reduce systemic inflammation in T2DM patients, potentially lowering risks for other serious conditions like cardiovascular disease.
Evaluation of type 1 diabetes' partial clinical remission after three years of heterologous adipose tissue derived stromal/stem cells transplantation associated with vitamin D supplementation.
Diabetol Metab Syndr
May 2024
Department of Internal Medicine, Nutrology Section, Universidade Federal do Rio de Janeiro (UFRJ), Av Professor Rodolpho Paulo Rocco 255, 22440035, Rio de Janeiro, RJ, Brazil.
Background: Mesenchymal stem cell infusion and vitamin D supplementation may have immunomodulatory actions that could prolong the preservation of residual insulin secretion in patients with type 1 diabetes (T1D). Intervention with these agents after onset of T1D could favor the development of a remission phase, with potential clinical impact. We aimed to compare the presence of clinical remission (CR), glycemic control and daily insulin requirement at 6, 12, 18, 24 and 36 months after the diagnosis of T1D using IDAA1c in patients who received therapy with adipose tissue-derived mesenchymal stem cell (ASC) infusion and vitamin D supplementation and a control group.
View Article and Find Full Text PDFGestational and neonatal outcomes of women with partial Dunnigan lipodystrophy.
Front Endocrinol (Lausanne)
April 2024
Brazilian Group for the Study of Inherited and Acquired Lipodystrophies (BRAZLIPO), Fortaleza, Brazil.
Article Synopsis
- Lipodystrophies are disorders that cause the selective loss of fat tissue, leading to increased risks of insulin resistance and related health issues, particularly in women with familial partial lipodystrophy type 2 (FPLD2), who also often face complications with pregnancy and gynecological conditions like PCOS.
- The study conducted a retrospective analysis of 8 women diagnosed with FPLD2 who had pregnancies, examining their pregnancy outcomes and associated complications.
- Results indicated significant fetal complications, including high rates of gestational diabetes, preeclampsia, miscarriages, and other neonatal issues, although no cases of infertility were reported.
Intake of Table Sugar and Their Corresponding Food Sources in Adults from the 2017-2018 Brazilian National Dietary Survey.
Nutrients
April 2024
Instituto Pensi, Fundação José Luiz Egydio Setubal, Hospital Infantil Sabará, São Paulo 01227-200, Brazil.
Excessive intake of free sugars is associated with adverse health outcomes. Table sugar is one of the main dietary sources of free sugars; however, the amount added by Brazilian consumers in their culinary preparations is unknown. The aims were to estimate the daily intake of table sugar (g/day), its contribution to total energy intake (E%) and the main food groups that contribute to the intake of this sugar in a nationwide multi-ethnic sample of Brazilian adults (2017-2018 Brazilian National Dietary Survey).
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