AI Article Synopsis
- The study examined how common late-onset hypogonadism is in men with osteoporosis compared to those with normal bone density.
- Findings revealed that 25% of men with osteoporosis had hypogonadism, compared to 12.2% of those with normal bone density, indicating a higher risk in osteoporotic men.
- The questionnaire's first question about low libido was the best indicator of hypogonadism, highlighting its potential role in screening.
Article Abstract
Objective: To analyze the relative risk of late-onset hypogonadism in men with osteoporosis and the usefulness of screening questionnaires.
Methods: We correlated the Aging Male's Symptoms (AMS), Androgen Deficiency in Aging Male (ADAM) and International Index of Erectile Function (IIEF-5) questionnaires and the laboratory diagnosis of hypogonadism in 216 men aged 50-84 years (110 with osteoporosis and 106 with normal bone density, paired by age and ethnicity).
Results: Hypogonadism presented in 25% of the osteoporotic and in 12.2 % of normal bone density men (OR 2.08; IC95%: 1.14-3.79) and was associated with ADAM first question (low libido, p=0.013). Levels of TT below 400 ng/dl correlated with an AMS score above 26 (p=0.0278). IIEF-5 showed no correlation with testosterone levels.
Conclusion: Hypogonadism was 2.08 times more prevalent in osteoporotic men. The symptom that best correlated with late-onset hypogonadism was low libido (ADAM 1 positive).
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| http://dx.doi.org/10.1590/s0004-27302008000900006 | DOI Listing |
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