Emerging nanotechnologies pose a new set of challenges for researchers, governments, industries and citizen organizations that aim to develop effective modes of deliberation and risk communication early in the research and development process. These challenges derive from a number of issues including the wide range of materials and devices covered by the term 'nanotechnology', the many different industrial sectors involved, the fact that many areas of nanotechnology are still at a relatively early stage of development, and uncertainty about the environmental, health and safety impacts of nanomaterials. Public surveys have found that people in the United States and Europe currently view the benefits of nanotechnologies as outweighing their risks although, overall, knowledge about nanotechnology remains very low. However, surveys cannot easily uncover the ways that people will interpret and understand the complexities of nanotechnologies (or any other topic about which they know very little) when asked to deliberate about it in more depth, so new approaches to engaging the public are needed. Here, we report the results of the first comparative United States-United Kingdom public engagement experiment. Based upon four concurrent half-day workshops debating energy and health nanotechnologies we find commonalities that were unexpected given the different risk regulatory histories in the two countries. Participants focused on benefits rather than risks and, in general, had a high regard for science and technology. Application context was much more salient than nation as a source of difference, with energy applications viewed in a substantially more positive light than applications in health and human enhancement in both countries. More subtle differences were present in views about the equitable distribution of benefits, corporate and governmental trustworthiness, the risks to realizing benefits, and in consumerist attitudes.
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http://dx.doi.org/10.1038/nnano.2008.362 | DOI Listing |
JNCI Cancer Spectr
January 2025
Department of Epidemiology and Biostatistics, University of California, Irvine, CA, USA.
Background: Obesity, classified by body mass index (BMI), is associated with higher postmenopausal breast cancer (BCa) risk. Yet, the associations between abdominal visceral (VAT) and subcutaneous adipose tissue (SAT) with BCa are unclear.
Methods: We assessed BCa associations with abdominal VAT and SAT in a prospective cohort of postmenopausal women without a history of cancer and with 27 years follow-up (N = 9950), during which all new cancers were adjudicated.
Anal Methods
January 2025
Department of Chemistry, Capital Normal University, Beijing, 100048, China.
Catechins in tea, as promoters of human health, have attracted widespread attention. Herein, a dual-signal mode (colorimetric and fluorescence) sensor array for catechin species fingerprinting was built based on PtNi bunched nanoparticle (PtNi-BNP)--phenylenediamine (OPD)-HO system. PtNi-BNPs catalyze the reaction between OPD and HO to produce oxidized OPD (oxOPD) with both colorimetric (yellow) and fluorescent properties.
View Article and Find Full Text PDFPurpose: To compare remineralisation efficacy between silver diamine fluoride (SDF) combined with potassium iodide (KI) and sodium fluoride (NaF) varnish using hydroxyapatite (HAP) artificial white spot lesions (AWSLs) demineralisation model.
Materials And Methods: A total of 25 HAP disks was randomly divided into five groups (n = 5): baseline, AWSLs, deionized water (DW), SDF-KI or F-varnish. After AWSLs were developed, the specimen was treated with either deionized water, SDF-KI or F-varnish.
Adv Healthc Mater
January 2025
Department of Biological Sciences, KAIST Institute for the BioCentury, Center for Precision Bio-Nanomedicine, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Republic of Korea.
Renal ischemia/reperfusion injury (IRI) is a common form of acute kidney injury. The basic mechanism underlying renal IRI is acute inflammation, where oxidative stress plays an important role. Although bilirubin exhibits potent reactive oxygen species (ROS)-scavenging properties, its clinical application is hindered by problems associated with solubility, stability, and toxicity.
View Article and Find Full Text PDFFood Funct
January 2025
School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China.
: Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality worldwide, with dietary interventions showing promise in reducing CVD risk factors. Phytosterols (PSs) in plant-based foods may reduce CVD risk by lowering low-density lipoprotein cholesterol. However, the relationship between dietary PS intake and CVD outcomes remains inconclusive.
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