On a cold December day in 1650, 22-year-old Anne Greene was hanged in Oxford. When taken down after half an hour, she was found to show signs of life and over the next few days William Petty (1623-87), Thomas Willis (1621-75), Ralph Bathurst (1620-74) and Henry Clerke (1622-87) ministered to her full recovery. She was later pardoned of the charge of infanticide and, with the coffin wherein she had lain as a trophy, went into the country, became the subject not only of a prose and poetic narrative but also of a woodcut. Anne married happily, bore three children and lived until 1659. A combination of low-body temperature and external (pedal) cardiac massage after her failed execution, it is suggested, helped to keep her alive until the arrival of the physicians who had come to make an anatomical dissection but serendipitously won golden opinions.
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http://dx.doi.org/10.1258/jmb.2007.007041 | DOI Listing |
J Med Educ Curric Dev
February 2024
Department of Pediatrics, The University of New Mexico School of Medicine, Albuquerque, USA.
Objectives: There is little data evaluating procedural skills in current rural pediatric practices. In order to prepare a cadre of pediatricians to work in rural settings, we require an understanding of the unique procedural skills needed by rural pediatric providers. Our objective was to determine how often pediatricians performed various procedural skills, determine the importance of these skills to current practice, and how they differ between rural and urban pediatric providers.
View Article and Find Full Text PDFPrev Sci
November 2021
Department of Psychology, Virginia Commonwealth University VCU, Box 842018, 23284-2018, Richmond, USA.
We evaluated the impact of the Olweus Bullying Prevention Program (OBPP) in an 8-year study in urban middle schools that served primarily African American students living in low-income areas. Participants included 2755 students and 242 teachers. We evaluated the OBPP with a multiple-baseline experimental design where the order and intervention start time was randomly assigned for each school.
View Article and Find Full Text PDFPDA J Pharm Sci Technol
October 2021
School of Chemical and Pharmaceutical Sciences, TU Dublin-City Campus, Kevin Street, Dublin 8, Ireland.
Knowledge management (KM) is identified in ICH Q10 (), as a key enabler to the pharmaceutical quality system (PQS). ICH Q8 (), ICH Q11 (), and ICH Q12 () each build on the expectation that knowledge will be managed effectively in order to support and improve the product and process across the pharmaceutical product life cycle. However, in spite of the fact that KM was introduced in ICH Q10 over 10 years ago, there is ample evidence that it is not yet a mature discipline within the biopharmaceutical sector, and the authors suggest that this could hinder full realization of the potential benefits of ICH Q8, ICH Q11, and ICH Q12.
View Article and Find Full Text PDFPDA J Pharm Sci Technol
January 2021
School of Chemical and Pharmaceutical Sciences, TU Dublin-City Campus, Kevin Street, Dublin 8, Ireland.
In collaboration with the Pharmaceutical Regulatory Science Team (PRST), a research team based at the Technological University Dublin (TU Dublin) in Ireland, a research study exploring the need for developing quality risk management (QRM) role-based competencies as fundamental elements to realizing QRM's benefits was conducted. The research study followed a hybrid Delphi research methodology of which elements are presented in the paper titled "Quality Risk Management Competency Model-Case for the need for QRM Competencies." This paper presents the second part of the Delphi research methodology, focusing on the results of a detailed technical and behavioral competencies questionnaire and a proposed QRM role-based competency model.
View Article and Find Full Text PDFPDA J Pharm Sci Technol
September 2019
TU Dublin.
In collaboration with the Pharmaceutical Regulatory Science Team (PRST), a research team based at the Technological University Dublin (TU Dublin) in Ireland, a research study exploring the need for developing QRM role-based competencies, as fundamental elements to realizing Quality Risk Management 's benefits was conducted. The research study followed a hybrid Delphi research methodology of which elements are presented in paper titled ″Quality Risk Management Competency Model- Case for the need for QRM Competencies.″ This paper presents the second part of the Delphi research methodology, focusing on the results of a detailed technical and behavioral competencies questionnaire and a proposed QRM role-based competency model.
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