An 83-year-old man was admitted for right lower lobe pneumonia which did not improve after a 5-day outpatient treatment with amoxicillin/clavulinate and clarithromycin. An empiric treatment with levofloxacin was started with a significant improvement after 24 h of this treatment. On the third day of hospitalization, delirium developed, while the patient was afebrile and with normal blood oxygenation. Treatment with levofloxacin was stopped, and a complete resolution of the patient's delirium was observed 2 days later. To the best of our knowledge, this is the third case of levofloxacin-induced delirium described in the medical literature.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1007/s10072-009-0027-9 | DOI Listing |
Eur J Hosp Pharm
November 2019
Department of Pharmacy, Faculty of Medicine, University of Nis, Nis, Serbia.
We present a case which reports the occurrence of psychotic disorders after metronidazole and levofloxacin therapy in a chronic kidney patient while being treated for enterocolitis and urinary infection. A 48-year-old female was admitted to a hospital for the placement of a peritoneal dialysis catheter due to indicated peritoneal dialysis. During admission, symptoms of enterocolitis and urinary infection had occurred, so metronidazole and levofloxacin were introduced into therapy, respectively.
View Article and Find Full Text PDFJ Clin Neurosci
August 2019
Department of Internal Medicine A, Bnai Zion Medical Center, Haifa, Israel; Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Delirium is the most frequent complication of hospitalization for elders and a potentially devastating problem. It is accompanied by high morbidity and mortality rate, and despite sensitive methods for its detection, delirium often is unrecognized and is missed by clinicians in up to 70% of delirious patients. Medications are considered one of the most common causes of delirium with sedatives, narcotics, dihydroperidines, antihistamines, and anticholinergics are most often implicated in its causation.
View Article and Find Full Text PDFJ Clin Med Res
September 2018
Department of Internal Medicine A, Bnai Zion Medical Center, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Delirium is considered as the most common complication afflicting hospitalized elderly patients, accompanied by high morbidity and mortality rate; and despite its high prevalence, it often remains unrecognized. Drug-induced delirium is a well-known entity with sedatives, narcotics and anticholinergics most often implicated in its causation. Delirium attributed to antibiotics, mainly cephalosporins and macrolids, has been infrequently reported, and until yet only seven cases of levofloxacin-induced delirium have been described in the medical literature.
View Article and Find Full Text PDFIndian J Palliat Care
February 2015
Department of Palliative Medicine, Tata Memorial Centre, Mumbai, Maharashtra, India.
Levofloxacin is a commonly prescribed antibiotic for managing chest and urinary tract infections in a palliative care setting. Incidence of Levofloxacin-associated anaphylaxis is rare and delirium secondary to Levofloxacin is a seldom occurrence with only few published case reports. It is an extremely rare occurrence to see this phenomenon in combination.
View Article and Find Full Text PDFMed J Armed Forces India
October 2013
Commandant, MH Gwalior, Gwalior 474006, India.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!