Riga-Fede disease RFD is an extremely rare, benign inflammatory disorder characterized by reactive, traumatic ulceration of the oral mucosa especially located on the tongue. It is most commonly associated with natal or neonatal teeth in newborns. Mucosal lesions are often caused by repetitive traumatic damage due to backward and forward motions of the tongue over the lower incisors. Failure to diagnose and treat these lesions properly may result in inadequate food intake, growth retardation and permanent lingual deformity. We report a 15-month-old healthy infant with tongue ulcer diagnosed as RFD based on history and clinical features.
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http://dx.doi.org/10.1111/j.1365-2230.2008.02796.x | DOI Listing |
Cureus
August 2024
Oral Medicine and Radiology, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Laryngoscope
November 2024
Department of Otolaryngology-Head & Neck Surgery, Eastern Virginia Medical School, Norfolk, Virginia, U.S.A.
In this case series, we present four unique cases of Riga-Fede disease (RFD), a rare disorder characterized by mucosal trauma as a result of repetitive tongue protrusion against the incisors, leading to the development of a large oral mass/ulceration. Due to the rapid development and growth of these lesions mimicking malignancy, it is important for the general and pediatric otolaryngologist to correctly diagnose and treat this benign disorder. This series highlights the variable clinical presentations, along with comorbidities of RFD, as well as the importance of interdisciplinary care between the pediatric otolaryngologist and pediatric dentist in its management.
View Article and Find Full Text PDFPediatr Dermatol
November 2023
Department of Dermatology and Venereology, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, Odisha, India.
Curr Pediatr Rev
October 2024
School of Dentistry, Department of Pediatric Dentistry, University of Texas Health Science Center at Houston; Private Practice: Grand Parkway Pediatric Dental, Richmond, TX, USA.
J Stomatol Oral Maxillofac Surg
October 2024
Department of Pathology, Saint-Luc University Clinics, Université Catholique de Louvain, Belgium. Electronic address:
Traumatic Ulcerative Granuloma with Stromal Eosinophilia (TUGSE)/Riga Fede disease is a rare mucosal and submucosal benign reactive inflammatory process, usually involving the tongue. Trauma is believed to be a major factor amongst the multiple pathogenic mechanisms that have been hypothesized in TUGSE. The lesion presents as an isolated indurated or even ulcerated mass, which may mimic, clinically a squamous cell carcinoma (SCC).
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