AI Article Synopsis

  • The field of biomaterials is shifting towards strategies that modulate the immune response, though current methods only target specific aspects of inflammation.
  • Certain bacteria and viruses effectively evade the immune system, which can inspire new biomimetic designs in materials.
  • The review discusses the immune evasion tactics of these pathogens and suggests future directions for creating biomaterials that can similarly evade immune responses.

Article Abstract

The field of biomaterials has begun to focus upon materials strategies for modulating the immune response. While certain approaches appear promising, they are currently limited to isolated facets of inflammation process. It is well documented that both bacteria and viruses have highly developed methods for evading the immune system, providing inspiration for a more biomimetic approach to materials design. This review presents the immune evasive tactics employed by viruses and bacteria, and offers suggestions for future directions that apply these principles to design of immune evasive biomaterials.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673477PMC
http://dx.doi.org/10.1016/j.biomaterials.2008.11.025DOI Listing

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