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Counterpoint: challenges and limitations of transcatheter aortic valve implantation for aortic regurgitation.
Heart
December 2021
Department of Cardiology, Saint Luke's Hospital, Kansas City, Missouri, USA
Article Synopsis
- TAVI is a heart procedure for fixing a valve called the aortic valve, but it's rarely used for a problem called aortic regurgitation (AR) in the USA.
- There are no approved devices specifically for AR, and other medical studies show that TAVI doesn't work as well for AR as it does for related conditions like aortic stenosis (AS).
- Newer devices like the JenaValve and J-Valve are being developed that might work better for AR, but more research is needed to prove they are safe and effective.
Organismal Responses to Hypoxemic Challenges.
Adv Exp Med Biol
January 2016
Departments of Environmental Health Sciences, The Johns Hopkins University Medical Institutions, Baltimore, MD, 21205, USA,
Article Synopsis
- This study examined how carotid bodies (CBs) and aortic bodies (ABs) respond to different types of low oxygen levels in anesthetized cats, specifically focusing on two conditions: hypoxic hypoxia (HH) and carbon monoxide hypoxia (COH).
- The researchers recorded various physiological responses, including cardiac output and vascular resistance in different organs, to investigate how these bodies maintain blood flow during hypoxemia.
- Findings indicated that HH was more effective in maintaining blood pressure and organ perfusion, while the role of ABs in regulating pulmonary circulation and local vasodilation was particularly highlighted.
Transcatheter aortic valve replacement (TAVR) has transformed the treatment of aortic stenosis in high-risk older adults in Europe and has begun to do so in the United States. Recent Food and Drug Administration approval of the Edwards Lifesciences SAPIEN Transcatheter Heart Valve (Irvine, Calif) in inoperable and high-risk patients led to enthusiasm for widespread implementation of this technology. Experts have highlighted the central role of the multidisciplinary heart team in implementing a successful TAVR program.
View Article and Find Full Text PDFCOUNTERPOINT: Aortic valve replacement: size does matter.
J Thorac Cardiovasc Surg
February 2009
Division of Cardiovascular Surgery, Peter Munk Cardiovascular Centre, Toronto General Hospital and the University of Toronto, Toronto, Ontario, Canada.
Interposed abdominal compression as an adjunct to cardiopulmonary resuscitation.
Am Heart J
February 1994
Hillenbrand Biomedical Engineering Center, Purdue University, West Lafayette, IN 47907.
The addition of IAC to otherwise standard CPR provides for the application of external pressure over the abdomen in counterpoint to the rhythm of chest compression. Interposed abdominal compression is a simple manual technique that can supplement the use of adrenergic drugs to increase both coronary perfusion pressure and total blood flow during CPR. Mechanistically, manual abdominal compressions induce both central aortic and central venous pressure pulses.
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