We show the use of a dimensionless parameter alpha h, in properly downscaling a parallel-plate flow chamber system for flow stimulation of bone cells under microgravity. The proper experimental regime for exposing cells to predictable levels of dynamic fluid shear stress requires: 1) alpha h < 2, based on the consequent quasi-parabolic form of the velocity profile in this regime, and 2) fo m
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Article Synopsis
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- The upper layer is a conducting fluid, while the lower layer is nonconducting, and the analysis involves mathematical techniques like perturbation expansion.
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