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Expansion of interventional endoscopy and day-case procedures: A nationwide longitudinal study of gastrointestinal endoscopy in France.
Clin Res Hepatol Gastroenterol
November 2024
Gastroenterology Department, Brest University Hospital, Brest, France; LaTIM, UMR 1101, Brest University Hospital, Brest, France. Electronic address:
Background: An accurate assessment of the evolution of GI endoscopy volumes is warranted to identify long-term trends and to help anticipate training, infrastructure and human resource needs. The main objective of this longitudinal study was to evaluate the evolution of GI endoscopy in France.
Methods: This retrospective study consisted of a cross-sectional analysis repeated each year from 2008 to 2018 using data from a national health database related to hospital admissions.
Systematic analysis of read-across adaptations in testing proposal evaluations by the European Chemicals Agency.
ALTEX
November 2024
Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
An essential aspect of the EU's "Registration, Evaluation, Authorisation and Restriction of Chemicals" (REACH) regulation is the European Chemicals Agency's (ECHA) evaluation of testing proposals submitted by registrants to address data gaps. Registrants may propose adaptations, such as read-across, to waive standard testing; however, it is widely believed that ECHA often finds justifications for read-across hypotheses inadequate. From 2008 to August 2023, 2,630 testing proposals were submitted to ECHA; of these, 1,538 had published decisions that were systematically evaluated in this study.
View Article and Find Full Text PDFIntegration of palliative rehabilitation in cancer care: a multinational mixed method study.
BMC Palliat Care
November 2024
Centre for Crisis Psychology, University of Bergen, Bergen, Norway.
Background: Incurable cancer is a major contributor to societal suffering and disability, and palliative rehabilitation is recommended to be integrated within and between cancer services at all healthcare levels. However, little knowledge exists on how integration of palliative rehabilitation in cancer is understood and achieved in clinical practice. INSPIRE (Integrated short-term palliative rehabilitation to improve quality of life and equitable care access in incurable cancer) is a large European-funded project that aims to promote quality of life through a novel rehabilitation model for people disabled by advanced cancer.
View Article and Find Full Text PDFDevelopment of an intraductal papillary mucinous neoplasm malignancy prediction scoring system.
PLoS One
October 2024
Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Despite the presence of various guidelines, diagnosing malignant intraductal papillary mucinous neoplasm (IPMN) continues to pose challenges. Furthermore, although endoscopic ultrasonography (EUS) offers high-resolution images, it has not yet recognized as the primary tool for malignancy diagnosis. The study objective was to develop a simplified and user-friendly scoring system to improve the diagnostic accuracy of malignant IPMNs.
View Article and Find Full Text PDFEndoscopic Retrograde Cholangio-Pancreatography and Endoscopic Ultrasound in the Management of Paediatric Acute Recurrent Pancreatitis and Chronic Pancreatitis.
J Clin Med
September 2024
Institute of Liver Studies, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Article Synopsis
- The study evaluates the effectiveness and safety of ERCP (endoscopic retrograde cholangio-pancreatography) and EUS (endoscopic ultrasound) in children with chronic and acute recurrent pancreatitis, analyzing data from 2008 to 2022.
- A total of 222 ERCP procedures were conducted, showing high technical success (98%), significant improvements in stricture resolution (63%), and a low adverse event rate (3.6%), along with substantial pain relief for 76% of patients.
- Additionally, 54 EUS procedures highlighted low complication rates (2.4%), confirming that both ERCP and EUS are safe and beneficial for paediatric patients, mirroring findings in adults.
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