A meta-analysis of mini-open versus standard open and laparoscopic living donor nephrectomy.

Transpl Int

Department of Biosurgery and Surgical Technology, Imperial College London, St Mary's Hospital, London, UK.

Published: April 2009

AI Article Synopsis

  • Mini-open donor nephrectomy (MODN) combines benefits of both standard open (SODN) and laparoscopic (LDN) techniques, offering a middle ground for kidney donation.
  • A review of nine studies involving 1,038 patients found MODN has a shorter hospital stay (1.67 days) and faster return to work (5 weeks) compared to SODN, along with lower overall complications.
  • While MODN showed significant time advantages over LDN regarding operation and warm ischemia times, it required slightly more analgesia, with no major differences in blood loss or complications between the techniques.

Article Abstract

Mini-open donor nephrectomy (MODN) potentially combines advantages of standard open (SODN) and laparoscopic techniques (LDN). This article is a comparison of these techniques. A literature search was performed for studies comparing MODN with SODN or LDN. Nine studies met our selection criteria. Of the 1038 patients, 433 (42%) underwent MODN, 389 (37%) SODN and 216 (21%) LDN. MODN versus SODN: Operative time (P = 0.17), warm ischemia time (P = 0.20) and blood loss (P = 0.30) were not significantly different. Hospital stay and time to return to work were shorter for MODN by 1.67 days (P < 0.001) and 5 weeks (P = 0.03). Analgesia requirement and overall complications were less in the MODN group (P < 0.001) and (P = 0.03). Ureteric complications (P = 0.21) and 1-year graft survival (P = 0.28) were not significantly different. MODN versus LDN: Operative and warm ischemia times were significantly shorter for the MODN by 55 min (P = 0.005) and 147 s (P < 0.001). Analgesia requirement was greater for the MODN group by 9.62 mEq morphine (P = 0.04). No significant differences were found for blood loss (P = 0.8), hospital stay (P = 0.35), donor complications (P = 0.40) or ureteric complications (P = 0.83). MODN appears to provide advantages for the donor in comparison to SODN and also has a shorter operative time when compared with the LDN.

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http://dx.doi.org/10.1111/j.1432-2277.2008.00828.xDOI Listing

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