Infective endocarditis (IE) is an uncommon but life-threatening infection during pregnancy. Although there have been several reports of endocarditis caused by Salmonella typhi, to our knowledge it has not been reported as a cause of endocarditis during pregnancy. We report a case of 27-year-old pregnant woman with aortic valve IE caused by S. typhi, who had moderate mitral stenosis and aortic regurgitation. During pregnancy, fever, increase in sedimentation should always alert the physician about the possibility of IE, especially in the presence of predisposing clinical conditions. Whenever possible, transesophageal echocardiographic evaluation should be performed because transthoracic echocardiography might not always demonstrate vegetation as in the present case.
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