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Intracranial solitary juvenile xanthogranuloma in an infant. | LitMetric

Intracranial solitary juvenile xanthogranuloma in an infant.

World J Pediatr

Department of Pediatric Neurosurgery, Xin Hua Hospital Affiliated to Shanghai Jiaotong University, Shanghai, 200092, China.

Published: February 2009

AI Article Synopsis

  • Juvenile xanthogranuloma (JXG) is a rare histiocyte proliferation disorder that usually manifests as a single skin lesion, but can occasionally involve other systems, leading to serious complications.
  • A case study involving a 5-month-old boy revealed a significant brain mass, despite an initially unremarkable exam except for an elevated anterior fontanel.
  • Surgical removal of the tumor, which included affected meninges, confirmed the diagnosis of JXG and highlighted that complete excision can potentially be a cure if vital signs and neurological functions remain stable.

Article Abstract

Background: Juvenile xanthogranuloma (JXG) is a disorder of histiocyte proliferation. Most cases present with a solitary cutaneous lesion. JXG with systemic involvement is rare with significant morbidity. Intracranial solitary JXG may be misdiagnosed before operation.

Methods: A 5-month-old boy showed an elevated anterior fontanel but no other abnormalities on admission. Brain MRI showed a large mass in the right parietal region.

Results: The tumor was removed with the encroached meninges. A JXG in the right parietal region was diagnosed pathologically.

Conclusion: Total excision of the tumor may be curative with a prerequisite of ensuring normal vital signs and nervous function.

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12519-009-0015-4DOI Listing

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