Background: The alterations of the glutathione peroxidase enzyme complex system occur in physiological conditions such as aging and oxidative stress consequent to strenuous exercise.
Methods: Authors optimize the spectrophotometric method to measure glutathione peroxidase activity in rat red blood cell membranes.
Results: The optimization, when applied to age paired rats, both nulligravid and pregnant, shows that pregnancy induces, at seventeen d of pregnancy, an increase of both reactive oxygen substance concentration in red blood cells and membrane glutathione peroxidase activity.
Conclusion: The glutathione peroxidase increase in erythrocyte membranes is induced by systemic oxidative stress long lasting rat pregnancy.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657797 | PMC |
| http://dx.doi.org/10.1186/1477-7827-7-7 | DOI Listing |
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