Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are global epidemics incurring significant morbidity and mortality. The combination presents many diagnostic challenges. Clinical symptoms and signs frequently overlap. Evaluation of cardiac and pulmonary function is often problematic and occasionally misleading. Echocardiography and pulmonary function tests should be performed in every patient. Careful interpretation is required to avoid misdiagnosis and inappropriate treatment. Airflow obstruction, in particular, must be demonstrated when clinically euvolaemic. Very high and very low concentrations of natriuretic peptides have high positive and negative predictive values for diagnosing HF in those with both conditions. Intermediate values are less informative. Both conditions are systemic disorders with overlapping pathophysiological processes. In patients with HF, COPD is consistently an independent predictor of death and hospitalization. However, the impact on ischaemic and arrhythmic events is unknown. Greater collaboration is required between cardiologists and pulmonologists to better identify and manage concurrent HF and COPD. The resulting symptomatic and prognostic benefits outweigh those attainable by treating either condition alone.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639415 | PMC |
http://dx.doi.org/10.1093/eurjhf/hfn013 | DOI Listing |
The hemodynamic definitions of pulmonary hypertension consider resistive loading (pulmonary vascular resistance [PVR]), but there are increasing evidence that pulsatile loading (pulmonary artery compliance [PAC]) has functional and prognostic importance. The aims of the present study on patients with left heart disease, were to evaluate a novel echocardiographic right ventricular (RV) afterload score and to investigate its relation to risk of mortality or implantation of a left ventricular assist device. Patients ( = 220) with left ventricular ejection fraction < 50% consecutively referred for heart transplant or heart failure workup underwent echocardiography and right heart catheterization.
View Article and Find Full Text PDFInt J Cardiol Congenit Heart Dis
June 2023
Adult Congenital Heart Disease Unit. Cardiology Department. Vall d'Hebron University Hospital, Barcelona, Spain.
Nutrition is the cornerstone of a healthy life and is crucial for the prevention of cardiovascular disease. Patients with congenital heart disease (CHD) are prone to nutrition disorders, including abnormalities in body composition such as overweight or obesity which, along with other classic cardiovascular risk factors, places our increasing and aging adult CHD (ACHD) population at a higher risk for acquired cardiovascular disease. These patients are also at risk of cachexia or sarcopenia as well as macronutrient and micronutrient deficiencies derived from the development of heart failure as a complication of their underlying cardiac disease.
View Article and Find Full Text PDFInt J Cardiol Congenit Heart Dis
June 2023
Department of Cardiology, University Medical Centre Ljubljana, Zaloska 2, 1000, Ljubljana, Slovenia.
Despite striking improvement in survival of patients with congenital heart disease (CHD), the risk of long-term complications remains high. Stroke and systemic embolism are common and potentially devastating complications that significantly affect morbidity and mortality in CHD. The risk of stroke in adult congenital heart disease (ACHD) is higher than in the general population, patients are affected at an earlier age, and the risk continues to increase with age.
View Article and Find Full Text PDFInt J Cardiol Congenit Heart Dis
June 2023
Heart Research, Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia.
Background: Patients with single ventricle (SV) without Fontan palliation are uncommon, and their long-term outcomes remain unclear.
Methods: Retrospective study of 35 adult patients with SV without Fontan from two tertiary centers. Primary outcome was mortality.
Int J Cardiol Congenit Heart Dis
September 2024
Congenital and Structural Cardiology, University Hospitals Leuven, Leuven, Belgium.
Background: Timely diagnosis of heart failure (HF) in patients with a systemic right ventricle (sRV) is difficult but important since clinical deterioration is fast once HF develops. We aimed to compare echocardiography and biomarker profile between sRV patients with and without HF and patients with a systemic left ventricle diagnosed with HF (sLV-HF).
Methods And Results: Eighty-seven sRV patients and 30 sLV-HF patients underwent echocardiographic evaluation and blood sampling.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!