Objective: To study whether levels of transrenal DNA (Tr-DNA) are influenced by the presence of urinary tract infections (UTI).
Methods: Tr-DNA concentrations were measured in 124 donors and 55 patients with UTI. Two methods for DNA extraction were compared.
Results: UTI patients showed higher concentrations than the donors (normal range: 0-147 GE/mL). QIAamp MiniElute Virus Spin Kit was more efficient than QIAamp DNA Blood Mini Kit.
Conclusion: Increased concentrations of Tr-DNA urine DNA are shown in presence of UTI.
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| http://dx.doi.org/10.1016/j.clinbiochem.2008.12.021 | DOI Listing |
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