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White-light crosslinkable milk protein bioadhesive with ultrafast gelation for first-aid wound treatment.
Biomater Res
February 2023
Institute of Dairy Science, College of Animal Sciences, Zhejiang University, 310058, Hangzhou, China.
Background: Post-traumatic massive hemorrhage demands immediately available first-aid supplies with reduced operation time and good surgical compliance. In-situ crosslinking gels that are flexibly adapting to the wound shape have a promising potential, but it is still hard to achieve fast gelation, on-demand adhesion, and wide feasibility at the same time.
Methods: A white-light crosslinkable natural milk-derived casein hydrogel bioadhesive is presented for the first time.
Visual Detection of Multiple Nucleic Acids in a Capillary Array.
J Vis Exp
November 2017
Key Laboratory of Systems Biomedicine (Ministry of Education), Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University; State Key Laboratory of Oncogenes and Related Genes; School of Biomedical Engineering, Shanghai Jiao Tong University;
Multi-target, short time, and resource-affordable methodologies for the detection of multiple nucleic acids in a single, easy to operate test are urgently needed in disease diagnosis, microbial monitoring, genetically modified organism (GMO) detection, and forensic analysis. We have previously described the platform called CALM (Capillary Array-based Loop-mediated isothermal amplification for Multiplex visual detection of nucleic acids). Herein, we describe improved fabrication and performance processes for this platform.
View Article and Find Full Text PDFThe emerging roles of clusterin on reduction of both blood retina barrier breakdown and neural retina damage in diabetic retinopathy.
Discov Med
April 2016
Department of Ophthalmology, Shanghai Tenth People's Hospital, Tongji University, Shanghai 200072, China.
Previous proteomic studies revealed that intravitreous clusterin was decreased in diabetic retinopathy (DR) patients. We explored the role of clusterin in reduction of both blood retina barrier (BRB) breakdown and neural retina damage in early DR. Immunofluorescent staining of proliferated diabetic retinopathy (PDR) membranes was performed to detect endogenous clusterin, and intravitreous injection of clusterin (CLU group) or PBS (DR group) to streptozotocin-induced diabetic rats was conducted.
View Article and Find Full Text PDFChronic conditions and household preparedness for public health emergencies: Behavioral Risk Factor Surveillance System, 2006-2010.
Prehosp Disaster Med
February 2014
1 National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia USA.
Introduction: Individuals with chronic conditions often experience exacerbation of those conditions and have specialized medical needs after a disaster. Less is known about the level of disaster preparedness of this particular population and the extent to which being prepared might have an impact on the risk of disease exacerbation. The purpose of this study was to examine the association between self-reported asthma, cardiovascular disease, and diabetes and levels of household disaster preparedness.
View Article and Find Full Text PDFPocket flashlight-elicited Quincke pulse for aortic dissection diagnosis.
Korean J Intern Med
September 2013
Department of Cardiology, Cardiovascular Center, St. Luke's International Hospital, Tokyo, Japan.
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