AI Article Synopsis
- The study aimed to evaluate the effectiveness of multiecho T2* mapping in detecting reperfusion hemorrhage after percutaneous coronary intervention for heart attacks, while also examining its impact on measuring the ischemic area at risk (IAR).
- Fifteen patients underwent imaging an average of 3.2 days post-procedure, revealing that a hemorrhage area of about 5% significantly correlated with infarct and obstruction volumes.
- The findings indicated that a 5% or lower hemorrhage led to a substantial underestimation of IAR by 50%, highlighting the importance of accurate boundary detection for assessment in the presence of hemorrhage.
Article Abstract
Research ethics committee approval and informed consent were obtained. The purpose of this study was to assess the feasibility of multiecho T2* mapping of the heart for detecting reperfusion hemorrhage following percutaneous primary coronary intervention (PPCI) for acute myocardial infarction, and to measure the effect of hemorrhage on quantifying the ischemic area at risk (IAR) on T2-weighted magnetic resonance images. Fifteen patients (mean age, 59 years; 13 men, two women) were imaged a mean of 3.2 days following PPCI. The mean area of hemorrhage, indicated by a T2* decay constant of less than 20 msec, was 5.0% +/- 4.9 (standard deviation) at the level of the infarct and this correlated with the infarct (r(2) = 0.76, P < .01) and microvascular obstruction (r(2) = 0.75, P < .01) volumes. When 5% or less hemorrhage was present, the IAR was underestimated by 50% at a standard deviation threshold level of five, compared with a boundary detection tool (21.8% vs 44.0%, P < .05). T2* mapping is feasible for quantifying post-reperfusion hemorrhage and boundary detection is required to accurately assess the IAR when hemorrhage is present.
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| http://dx.doi.org/10.1148/radiol.2503081154 | DOI Listing |
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