Noninvasive portable sensors are becoming popular in biomedical engineering practice due to its ease of use. This paper investigates the estimation of human oxygen uptake (VO(2)) of treadmill exercises by using multiple portable sensors (wireless heart rate sensor and triaxial accelerometers). For this purpose, a multivariable Hammerstein model identification method is developed. Well designed PRBS type of exercises protocols are employed to decouple the identification of linear dynamics with that of nonlinearities of Hammerstein systems. The support vector machine regression is applied to model the static nonlinearities. Multivariable ARX modelling approach is used for the identification of dynamic part of the Hammerstein systems. It is observed the obtained nonlinear multivariable model can achieve better estimations compared with single input single output models. The established multivariable model has also the potential to facilitate dynamic estimation of energy expenditure for outdoor exercises, which is the next research step of this study.
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http://dx.doi.org/10.1109/IEMBS.2008.4649690 | DOI Listing |
JACS Au
January 2025
Department of Physics, Freie Universität Berlin, Arnimallee 14, Berlin 14195, Germany.
Interactions of polyelectrolytes (PEs) with proteins play a crucial role in numerous biological processes, such as the internalization of virus particles into host cells. Although docking, machine learning methods, and molecular dynamics (MD) simulations are utilized to estimate binding poses and binding free energies of small-molecule drugs to proteins, quantitative prediction of the binding thermodynamics of PE-based drugs presents a significant obstacle in computer-aided drug design. This is due to the sluggish dynamics of PEs caused by their size and strong charge-charge correlations.
View Article and Find Full Text PDFJ Mammal
February 2025
Centre for Biodiversity Conservation Research, Ebenezer Laing Road, GA 490-3153, University of Ghana, Legon, P.O. Box LG 67, Accra, Ghana.
We provide the first estimates of survival and reproductive rates for a population of the Gambian Epauletted Fruit Bat in Ghana. We focused on a large colony of ca. 5,000 bats over 3 years to estimate population parameters including population size, birth rates, survival, and sex ratios for this species.
View Article and Find Full Text PDFMalar J
January 2025
MIVEGEC, Univ. Montpellier, CNRS, IRD, Montpellier, France.
Background: The increasing availability of electronic health system data and remotely-sensed environmental variables has led to the emergence of statistical models capable of producing malaria forecasts. Many of these models have been operationalized into malaria early warning systems (MEWSs), which provide predictions of malaria dynamics several months in advance at national and regional levels. However, MEWSs rarely produce predictions at the village-level, the operational scale of community health systems and the first point of contact for the majority of rural populations in malaria-endemic countries.
View Article and Find Full Text PDFAntimicrob Resist Infect Control
January 2025
Unit 37: Healthcare-Associated Infections, Surveillance of Antibiotic Resistance and Consumption, Department of Infectious Disease Epidemiology, Robert Koch Institute, Seestraße 10, 13353, Berlin, Germany.
Background: Antimicrobial resistance is a global threat to public health, with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecium (VREfm) being major contributors. Despite their clinical impact, comprehensive assessments of changes of the burden of bloodstream infections in terms of Disability-Adjusted Life Years (DALYs) and attributable deaths over time are lacking, particularly in Germany.
Methods: We used data from the Antimicrobial Resistance Surveillance system, which covered about 30% of German hospitals.
Sci Rep
January 2025
Department of Electrical and Computer Engineering, University of Texas at San Antonio, San Antonio, TX, 78249, USA.
The inherently stochastic nature of radiation emissions makes modeling background radiation structure a particularly challenging research area. In source identification scenarios, which are critical to nuclear security, the complexity of background radiation modeling is intensified by dynamically changing factors that influence radiation measurements. Consequently, accurately modeling and estimating background radiation can significantly improve our nuclear security capabilities by enhancing the detection of anomalies within radiation data.
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