The study of the mechanomyographic (MMG) signals of respiratory muscles is a promising technique in order to evaluate the respiratory muscles effort. A new approach for quantifying the relationship between respiratory MMG signals and respiratory effort is presented by analyzing the spatio-temporal patterns in the MMG signal using two non-linear methods: Rényi entropy and Lempel-Ziv (LZ) complexity analysis. Both methods are well suited to the analysis of non-stationary biomedical signals of short length. In this study, MMG signals of the diaphragm muscle acquired by means of a capacitive accelerometer applied on the costal wall were analyzed. The method was tested on an animal model (dogs), and the diaphragmatic MMG signal was recorded continuously while two non anesthetized mongrel dogs performed a spontaneous ventilation protocol with an incremental inspiratory load. The performance in discriminating high and low respiratory effort levels with these two methods was analyzed with the evaluation of the Pearson correlation coefficient between the MMG parameters and respiratory effort parameters extracted from the inspiratory pressure signal. The results obtained show an increase of the MMG signal Rényi entropy and LZ complexity values with the increase of the respiratory effort. Compared with other parameters analyzed in previous works, both Rényi entropy and LZ complexity indexes demonstrates better performance in all the signals analyzed. Our results suggest that these non-linear techniques are useful to detect and quantify changes in the respiratory effort by analyzing MMG respiratory signals.
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http://dx.doi.org/10.1109/IEMBS.2008.4649610 | DOI Listing |
Paediatr Drugs
January 2025
Child and Maternal Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia.
Despite significant global reductions in cases of pneumonia during the last 3 decades, pneumonia remains the leading cause of post-neonatal mortality in children aged <5 years. Beyond the immediate disease burden it imposes, pneumonia contributes to long-term morbidity, including lung function deficits and bronchiectasis. Viruses are the most common cause of childhood pneumonia, but bacteria also play a crucial role.
View Article and Find Full Text PDFmSphere
January 2025
Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA.
Existing genetic classification systems for porcine reproductive and respiratory syndrome virus type 2 (PRRSV-2), such as restriction fragment length polymorphisms and sub-lineages, are unreliable indicators of close genetic relatedness or lack sufficient resolution for epidemiological monitoring routinely conducted by veterinarians. Here, we outline a fine-scale classification system for PRRSV-2 genetic variants in the United States. Based on >25,000 U.
View Article and Find Full Text PDFBreathe (Sheff)
January 2025
Sakarya University of Applied Sciences, Faculty of Health Sciences, Department of Nursing, Internal Disease Nursing, Sakarya, Türkiye.
Nursing plays a critical role in delivering healthcare services. It is a health discipline encompassing both science and art, designed to support people from birth to the end of life, in health and illness. Nurses are required to identify the physical and psychological needs of individuals, families and society with a comprehensive, human-oriented approach and to meet these needs.
View Article and Find Full Text PDFNPJ Antimicrob Resist
February 2024
National Heart and Lung Institute, Imperial College London, London, UK.
Antimicrobial peptides (AMPs) are key components of innate immunity across all domains of life. Natural and synthetic AMPs are receiving renewed attention in efforts to combat the antimicrobial resistance (AMR) crisis and the loss of antibiotic efficacy. The gram-negative pathogen Pseudomonas aeruginosa is one of the most concerning infecting bacteria in AMR, particularly in people with cystic fibrosis (CF) where respiratory infections are difficult to eradicate and associated with increased morbidity and mortality.
View Article and Find Full Text PDFEur Respir Rev
January 2025
Dept of Public Health and Primary Care, Academic Centre for Nursing and Midwifery, KU Leuven - University of Leuven, Leuven, Belgium
Introduction: People with idiopathic pulmonary fibrosis (IPF) and other forms of progressive pulmonary fibrosis (PPF) have a high symptom burden and a poor health-related quality of life (HRQoL). Despite efforts to offer specialised treatment, clinical care for these patients remains suboptimal and several nonmedical needs remain unaddressed. Developing a core outcome set (COS) can help to identify a minimum set of agreed-upon outcomes that should be measured and acted-upon in clinical care.
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