The innovative arbitrary waveform defibrillator for animal research presented in this paper is based on two power linear amplifiers in bridge configuration. It is capable of delivering 10 J shocks of arbitrary shape and duration. The system can be used to test new waveforms by comparing them to traditional ones, in in-vitro experiments. The system is battery operated, has an isolated output, and is PC controlled. Loads with impedance ranging from 10 to 25 ohms can be connected. A maximum of +/-130 V, 10A can be delivered to the loads. Effective voltage and current are measured and collected in the PC. Examples of waveforms as well as preliminary results from experiments of isolated rabbit hearts are presented.
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http://dx.doi.org/10.1109/IEMBS.2008.4649223 | DOI Listing |
HardwareX
June 2024
Photon Science Institute, University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom.
Various applications require multi-channel high-voltage sources for their control, e.g. electrostatic adhesion, electrophoresis and artificial muscles such as piezoelectric, hydraulically amplified self-healing electrostatic(HASEL) and dielectric elastomer actuators(DEAs).
View Article and Find Full Text PDFMed Biol Eng Comput
December 2024
Department of Applied Physics III, Universidad de Sevilla, Camino de los Descubrimientos, S/N, 41092, Sevilla, Spain.
Neural electrostimulation has enabled different therapies to treat a number of health problems. For example, the cochlear implant allows for recovering the hearing function and deep brain electrostimulation has been proved to reduce tremor in Parkinson's disease. Other approaches such as retinal prostheses are progressing rapidly, as researchers continue to investigate new strategies to activate targeted neurons more precisely.
View Article and Find Full Text PDFA simple and straightforward technique is presented as a novel temporally controllable front-end for nanosecond very-high energy laser systems. It is based on an original utilization of a semiconductor optical amplifier (SOA) used as an intensity modulator. The essential characteristics of the component are analyzed in order to evaluate potential limitations.
View Article and Find Full Text PDFThe linear frequency swept light source is a critical device for several sensing applications, including FMCW LiDAR, with which the maximum sensing distance is determined by the coherence length of the light source and the spatial resolution is limited by the frequency scan nonlinearity. Here, we report what we believe to be a novel approach to generate highly coherent optical linear frequency sweeps (LFS) with a Fourier domain mode-locked (FDML) opto-electronic oscillator (OEO) deploying carrier suppressed single sideband (CS-SSB) modulation enabled by a dual-parallel Mach-Zehnder modulator (DP-MZM), with the coherence length determined by the fixed frequency laser used in the OEO, without the need of an expensive high-speed arbitrary waveform generator (AWG). Concurrently, a radio frequency (RF) LFS synchronized with the optical LFS is also generated with the FDML OEO.
View Article and Find Full Text PDFA novel, to our knowledge, approach for generating optical pulses with programmable positions in an actively mode-locked (AML) optical cavity is proposed and experimentally demonstrated. In the AML, active mode locking occurs when the cavity gain exceeds one, and the cavity round trip time equals integer multiples of the repetition period of the electrical driving signal. The generated optical pulses are present at the positions where the optical cavity operates at its maximum transmission points.
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