Hepatitis A vaccination coverage among adults aged 18-49 years in the United States.

Vaccine

Immunization Services Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mail Stop E-62, Atlanta, GA 30333, United States.

Published: February 2009

AI Article Synopsis

  • Hepatitis A is the most common type of hepatitis in the U.S., with a cyclical incidence pattern before the vaccine was introduced in 1996, and annual cases ranged from 22,000 to 36,000 from 1980 to 1995.
  • The study analyzed 2007 National Immunization Survey data, focusing on adults aged 18-49, to estimate self-reported hepatitis A vaccination coverage and identify associated factors.
  • In 2007, only 12.1% of adults aged 18-49 reported being vaccinated, with younger adults and those with public insurance more likely to be vaccinated, while coverage was significantly lower among Hispanics compared to non-Hispanic whites.

Article Abstract

Background: Hepatitis A is the most common type of hepatitis reported in the United States. Prior to hepatitis A vaccine introduction in 1996, hepatitis A incidence followed a cyclic pattern with peak incidence occurring every 10-15 years. During 1980-1995, between 22,000 and 36,000 hepatitis A cases were reported annually. Since 1996, hepatitis A vaccination recommendations have included adults at risk for infection and children living in communities with the highest disease rates. This study provides the first national estimates of self-reported hepatitis A vaccination coverage among persons aged 18-49 years in the United States.

Methods: We analyzed the 2007 National Immunization Survey-Adult (NIS-Adult) data with restrictions to individuals aged 18-49 years. National estimates of hepatitis A vaccination coverage were calculated based on self-report and multivariable logistic regression analysis was used to identify factors independently associated with hepatitis A vaccination status.

Results: Among adults aged 18-49 years, 12.1% (95% confidence interval, CI=9.9-14.8%) had received two or more doses of hepatitis A vaccine in 2007. Hepatitis A vaccination coverage was significantly higher among adults aged 18-29 years (15.6%) and adults aged 30-39 years (12.9%) compared with adults aged 40-49 years (8.3%). Coverage was significantly lower for Hispanics (7.1%) compared with non-Hispanic whites (12.5%). Characteristics independently associated with a higher likelihood of hepatitis A vaccination among persons aged 18-49 years included younger age groups, persons at or above poverty level, persons with public medical insurance, and persons who received influenza vaccination in the past season.

Conclusions: In 2007, self-reported hepatitis A vaccination coverage among adults aged 18-49 years was 12.1%. These data provide the first national hepatitis A vaccination coverage estimates among adults and are very important in planning and implementing strategies for increasing hepatitis A vaccination coverage among adults at risk for hepatitis A.

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Source
http://dx.doi.org/10.1016/j.vaccine.2008.12.054DOI Listing

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