Identification of sex chromosome mosaicism: is analysis of 20 metaphase cells sufficient?

Am J Med Genet A

Cytogenetics Laboratory, Mayo Clinic, Rochester, MN 55905, USA.

Published: February 2009

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.a.32625DOI Listing

Publication Analysis

Top Keywords

identification sex
4
sex chromosome
4
chromosome mosaicism
4
mosaicism analysis
4
analysis metaphase
4
metaphase cells
4
cells sufficient?
4
identification
1
chromosome
1
mosaicism
1

Similar Publications

Parental monitoring is a robust family-level predictor of youth well-being. Identification of variations by gender and/or race/ethnicity in parental monitoring has important implications for tailoring parenting practices. However, valid comparisons can only be conducted if cross-subpopulation measurement equivalence is established.

View Article and Find Full Text PDF

Identification of chromosomal abnormalities is an important issue in animal breeding and veterinary medicine. Routine cytogenetic diagnosis of domestic animals began in the 1960s with the aim of identifying carriers of centric fusion between chromosome 1 and 29 in cattle. In the 1970s, chromosome banding techniques were introduced, and in the 1980s, the first cytogenomic techniques, based on the development of locus- and chromosome-specific probes, were used.

View Article and Find Full Text PDF

Background: In a recent randomized trial, six months of financial incentives contingent for recent alcohol abstinence led to lower levels of hazardous drinking, while incentives for recent isoniazid (INH) ingestion had no impact on INH adherence, during TB preventive therapy among persons with HIV (PWH). Whether the short-term incentives influence long-term alcohol use and HIV viral suppression post-intervention is unknown.

Methods: We analyzed twelve-month HIV viral suppression and alcohol use in the Drinkers' Intervention to Prevent Tuberculosis study, a randomized controlled trial among PWH with latent TB and unhealthy alcohol use in south-western Uganda.

View Article and Find Full Text PDF

Background: The Russian military invasion of Ukraine has sparked Europe's largest forced displacement since World War II, bringing about significant health vulnerabilities for migrants and refugees. European health information systems lack comprehensive data coverage, especially in underrepresented migration stages like transit. This study aims to address this gap by analyzing data from INTERSOS clinics at the Moldovan and Polish borders with Ukraine to identify the common health conditions prompting people to seek healthcare services during transit.

View Article and Find Full Text PDF

Background: Lipid Accumulation Product (LAP), which is derived from measurements of waist circumference and triglyceride (TG) levels, serves as a comprehensive indicator of lipid accumulation. Emerging research indicates that lipid accumulation dysfunction might significantly contribute to the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Nevertheless, the investigation into the association between LAP and COPD risk is still insufficient, particularly in population-based research.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!