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Effectiveness and Safety of Dose-Specific DOACs in Patients With Atrial Fibrillation: A Systematic Review and Network Meta-Analysis.

Cardiovasc Ther

January 2025

College of Pharmacy and Institute of Pharmaceutical Science and Technology, Hanyang University, Ansan-si, Gyeonggi-do, Republic of Korea.

Dose adjustments of direct-acting oral anticoagulants (DOACs) for atrial fibrillation are based on pivotal clinical trials assessing their effectiveness and safety in controlled settings. However, the appropriateness of these dosing strategies in real-world practice is uncertain. The purpose of this study is to compare the effectiveness and safety of dose-specific DOACs with those of warfarin.

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A Study on Endometrial Polyps Recurrence Post-Hysteroscopic Resection: Identification of Influencing Factors and Development of a Predictive Model.

Ann Ital Chir

January 2025

Department of Obstetrics and Gynecology, Center for Reproductive Medicine, The Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, 322000 Yiwu, Zhejiang, China.

Aim: This study aimed to explore influencing factors and develop a predictive model of endometrial polyps (EP) recurrence after hysteroscopic resection.

Methods: This retrospective study included 180 patients who underwent hysteroscopic resection for EP between January 2021 to December 2023. The patients were divided into a modeling group (n = 135) and a validation group (n = 45) in a 3:1 ratio.

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Homodyne interferometers (HIs) utilize differential signaling to reduce common-mode noise and enhance measurement stability. However, their potential to improve measurement accuracy has not been thoroughly investigated. To address this gap, we reveal two unrecognized mechanisms enabled by differential-output signal (DS): self-compensation for odd-order periodic nonlinear error (PNE) and mitigation of PNE caused by ghost reflections.

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Optical misalignment between transmitter and receiver leads to power loss and mode crosstalk in a mode division multiplexing (MDM) free-space optical (FSO) link. We report both numerical simulations and experimental results on the propagation performance of two typical vector beams, C-point polarization full Poincaré beams (FPB), and V-point polarization cylindrical vector beams (CVB), compared to homogeneous polarization scalar vortex beams (SVB) under optical misalignment. The FSO communication performance under misalignment using different transmit beams is evaluated in terms of power loss, mode crosstalk, power penalty, etc.

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Background: Radiofrequency (RF) transmit arrays play a crucial role in various MRI applications, offering enhanced field control and improved imaging capabilities. Designing and optimizing these arrays, particularly in high-field MRI settings, poses challenges related to coupling, resonance, and construction imperfections. Numerical electromagnetic simulation methods effectively aid in the initial design, but discrepancies between simulated and fabricated arrays often necessitate fine-tuning.

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