AI Article Synopsis
- The study examined the relationship between alcohol consumption and fatty liver in Japanese individuals using both cross-sectional and longitudinal methods during health checkups from 2000 to 2005.
- The analysis included a large sample of participants, revealing that fatty liver prevalence was lower among occasional and moderate drinkers than non-drinkers, particularly in men.
- Overall, findings suggest that alcohol drinking might not be a significant risk factor for fatty liver in this population.
Article Abstract
The question of whether alcohol drinking is a risk factor for fatty liver as shown by ultrasonography was investigated by both cross-sectional and longitudinal approaches in Japanese undergoing a health checkup. In this cross-sectional study, 32,438 males (49.0 +/- 11.9 years old) and 31,009 females (48.2 +/- 11.6 years old) receiving a health checkup from 2000 to 2005 were included. Longitudinally, 5,444 males (49.8 +/- 10.7 years old) and 4,980 females (50.4 +/- 9.3 years old) participating in both 2000 and 2005 were included. Multiple logistic regression analyses were performed for both sexes, adjusted for age, BMI, and smoking. The prevalence of fatty liver in non-, occasional, daily moderate, and daily heavy drinkers was 28.5, 27.5, 18.7, and 19.1% in men and 12.4, 7.7, 5.4, and 6.7% in women, respectively (inverse association, P < or = 0.05 for both). Occasional, daily moderate, and daily heavy drinking in men and occasional and daily moderate drinking in women were inversely associated with fatty liver in the cross-sectional study. Daily moderate and heavy drinking appeared protective in men in the longitudinal study. Alcohol drinking may not be a major risk for fatty liver in Japanese undergoing a health checkup.
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| http://dx.doi.org/10.1007/s10620-008-0693-0 | DOI Listing |
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