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Task-Driven Tailored Covalent Organic Framework for Dynamic Capture of Trace Radioactive CH I under High-Flow Rate Conditions.
ACS Cent Sci
November 2024
State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China.
Article Synopsis
- The removal of radioactive gaseous iodine, especially methyl iodide, is essential for safe nuclear energy management and waste disposal, but effective capture methods are still being researched.* -
- This study used a "theory-first" approach to create a new material, piperazine-based covalent organic framework (Pip-COF), designed specifically for high capture efficiency of methyl iodide.* -
- Testing showed Pip-COF performs exceptionally well, capturing up to 39 mg/g at 75 °C and 78 mg/g at 25 °C, far exceeding previous materials, and the study highlights the importance of rational design in addressing environmental challenges.*
Effects of Ionizing Radiation on Flora Ten Years after the Fukushima Dai-ichi Disaster.
Plants (Basel)
January 2022
Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via di Motpellier 1, 00133 Rome, Italy.
The aim of this work is to analyze the effects of ionizing radiation and radionuclides (like Cs) in several higher plants located around the Fukushima Dai-ichi Nuclear Power Plant (FNPP), evaluating both their adaptive processes and evolution. After the FNPP accident in March 2011 much attention was focused to the biological consequences of ionizing radiation and radionuclides released in the area surrounding the nuclear plant. This unexpected mishap led to the emission of radionuclides in aerosol and gaseous forms from the power plant, which contaminated a large area, including wild forest, cities, farmlands, mountains, and the sea, causing serious problems.
View Article and Find Full Text PDFDevelopment of [I]I-EOE-TPZ and [I]I-EOE-TPZMO: Novel Tirapazamine (TPZ)-Based Radioiodinated Pharmaceuticals for Application in Theranostic Management of Hypoxia.
Pharmaceuticals (Basel)
January 2019
Department of Oncology, Cross Cancer Institute, Faculty of Medicine and Dentistry, University of Alberta, 11560 University Avenue, Edmonton, AB T6G 1Z2, Canada.
: Benzotriazine-1,4-dioxides (BTDOs) such as tirapazamine (TPZ) and its derivatives act as radiosensitizers of hypoxic tissues. The benzotriazine-1-monoxide (BTMO) metabolite (SR 4317, TPZMO) of TPZ also has radiosensitizing properties, and via unknown mechanisms, is a potent enhancer of the radiosensitizing effects of TPZ. Unlike their 2-nitroimidazole radiosensitizer counterparts, radiolabeled benzotriazine oxides have not been used as radiopharmaceuticals for diagnostic imaging or molecular radiotherapy (MRT) of hypoxia.
View Article and Find Full Text PDFStatistical and radiobiological analysis of the so-called thyroid stunning.
EJNMMI Res
December 2015
Nuclear medicine, Molecular Imaging, Radiotherapy and Oncology Unit (MIRO), IECR, Université Catholique de Louvain, Av. Hippocrate 10, 1200, Brussels, Belgium.
Background: The origin of the reduction in thyroid uptake after a low activity iodine scan, so-called stunning effect, is still controversial. Two explanations prevail: an individual cell stunning that reduces its capability to store iodine without altering its viability, and/or a significant cell-killing fraction that reduces the number of cells in the tissue still taking up iodine. Our aim is to analyze whether this last assumption could explain the observed reduction.
View Article and Find Full Text PDFThe Effect of Diagnostic Absorbed Doses from 131I on Human Thyrocytes in Vitro.
Int J Mol Sci
June 2015
Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, 93-338 Lodz, Poland.
Background: Administration of diagnostic activities of 131I, performed in order to detect thyroid remnants after surgery and/or thyroid cancer recurrence/metastases, may lead to reduction of iodine uptake. This phenomenon is called "thyroid stunning". We estimated radiation absorbed dose-dependent changes in genetic material, in particular in sodium iodide symporter (NIS) gene promoter, and NIS protein level in human thyrocytes (HT).
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