Symplastic glomus tumors are defined as glomus tumors with a high-grade nuclear pleomorphism in the absence of any other malignant features, such as large size, deep location, infiltrative growth, mitotic activity, or necrosis. Only 11 cases have been reported so far in the English literature. It could be a challenge for pathologists who have no experience with it because the tumor can show marked nuclear atypia and pleomorphism. Despite its high nuclear grade, a symplastic glomus tumor itself has a benign biologic behavior. Hereby, the authors report a case of a symplastic glomus tumor on the right index finger tip of a 44-year-old woman with a literature review.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/DAD.0b013e31818d3ac7 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Extradigital Symplastic Glomus Tumor and Review of the Literature.
Am J Dermatopathol
January 2025
Department of Dermatology, Vanderbilt University Medical Center, Nashville, TN.
Symplastic glomus tumors are a rare subtype of glomus tumor defined by nuclear atypia without additional markers of malignancy such as large size, deep location, or atypical/prevalent mitotic figures. Glomus tumors, including the symplastic subtype, most commonly present in the subungual area with rarer extradigital presentation. To our knowledge, there have been less than 25 cases of symplastic glomus tumors described in the literature.
View Article and Find Full Text PDFSymplastic Glomus Tumor: Pathologist's Challenge and Physician's Dilemma: A Case Report with Review.
Indian Dermatol Online J
August 2023
Department of Skin and Veneral Diseases, IMS and SUM Hospital, S'O'A (Deemed to be) University, Bhubaneswar, Odisha, India.
Glomus tumor is a distinct mesenchymal tumor of specialized perivascular smooth cell origin (pericyte), reminiscent of normal glomus body located in the fingers. It accounts for <2% of soft tissue tumors. Recently WHO categorized few unusual variants, of which symplastic glomus tumor is one.
View Article and Find Full Text PDF[Clinicopathological characterization of primary pulmonary and tracheal glomus tumors].
Zhonghua Bing Li Xue Za Zhi
December 2020
Department of Pathology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, China.
To investigate the clinical pathological features of primary pulmonary and tracheal glomus tumors. The clinical and pathological features of 11 cases (4 cases from Shanghai Pulmonary Hospital, Tongji University School of Medicine, China and 7 cases from Fudan University Shanghai Cancer Center, China) of respiratory glomus tumor diagnosed from 2010 to 2019 were analyzed, and reviewed in light of the relevant literature. In the 11 cases, there were 5 males and 6 females, with the onset ages of 29‒66 years (median age of 43).
View Article and Find Full Text PDF[Clinicopathologic features of glomus tumor of the kidney].
Zhonghua Bing Li Xue Za Zhi
August 2018
Department of Pathology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.
To investigate the clinicopathologic and differential diagnostic features of glomus tumor of the kidney. Four cases of glomus tumor of the kidney were collected from the archives of Peking University Third Hospital, the Second Hospital of Tianjin Medical University, Ningbo Yinzhou Second Hospital and Zhejiang Provincial People's Hospital between January 2012 to June 2017; the clinical and radiologic features, histomorphology, immunohistochemistry, ultrastucture and prognosis were analyzed and the relevant literature was reviewed. Patients consisted of 2 men and 2 women with ages ranging from 37 years to 66 years (mean 55 years).
View Article and Find Full Text PDFNail Unit Glomus Tumor with Myxoid and Symplastic Change Presenting with Longitudinal Erythronychia.
Dermatopathology (Basel)
June 2018
Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Glomus tumors are soft tissue neoplasms, which are most frequently encountered in the nail unit and generally straightforward to diagnose by histopathology. The typical clinical presentation is that of a circular violaceous or erythematous lesion within the nail bed. However, there are rare variants of glomus tumors which may pose diagnostic challenges because of the presence of unusual histologic features.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!