Treatment choices for oral cancer in cats. What is possible? What is reasonable?

Practical relevance Oral cancers are not the most common tumour in our domestic cats, but the death rate associated with cancer in this location is particularly high. This is largely because the cancer is discovered late in its development and also because of the severe debility it causes when the patient is unable or unwilling to eat and drink. Audience This review of malignant oral tumours (squamous cell carcinoma, oral sarcoma, oral melanoma and salivary adenocarcinoma) and benign oral tumours that may mimic malignant lesions is directed at all veterinarians that see older cats - both for ‘health and wellness’ as well as for more advanced treatment of already diagnosed neoplasia. Patient group As it is almost always older cats that are affected, patients will have a strong bond with their owners. These cats also often have unrelated intercurrent disease that may affect treatment choices, the way treatment is administered, and whether the owner chooses aggressive or palliative therapy. Evidence base While the literature on treatment of oral cancer in dogs is well established, until recently it was less so in cats. As researchers focus on treating cats with curative intent, as well as palliatively and supportively, the material available to guide veterinarians has also increased. This article evaluates the current literature from the author's perspective as an oncologist and a cat owner.