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The detection of synergy between meropenem and polymyxin B against meropenem-resistant Acinetobacter baumannii using Etest and time-kill assay. | LitMetric
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The detection of synergy between meropenem and polymyxin B against meropenem-resistant Acinetobacter baumannii using Etest and time-kill assay.

George A Pankey Deborah S Ashcraft

Diagn Microbiol Infect Dis

Infectious Disease Research, Ochsner Clinic Foundation, New Orleans, LA 70121, USA.

Published: February 2009

Time-kill assay and Etest testing for synergy of meropenem (MER) (1x MIC) plus polymyxin B (1/4, 1/2, and 1x MIC) were performed against 8 genetically unique MER-resistant clinical Acinetobacter baumannii isolates. Time-kill assay demonstrated synergy for all isolates, whereas Etest showed synergy in 5 isolates and indifference in 3.

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http://dx.doi.org/10.1016/j.diagmicrobio.2008.11.002DOI Listing

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