The aim of this study was to compare the effect of location and number of implants on the retention and stability of magnetically retained mandibular overdentures. Four groups of such prostheses were classified according to number and position of the implants in the canine, premolar, or molar regions. Significant differences in retention were observed when 6 magnets were used (4.66 +/- 0.45 N), whereas the lowest retention was obtained with 2 magnets (2.1 +/- 0.43 N). Only oblique stability was improved significantly when the number of implants was increased.
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Eur Spine J
January 2025
Department of Traditional Chinese Medicine, Dongguan Binhaiwan Central Hospital, Dongguan City, Guangdong Province, 523905, China.
Objective: To explore the efficacy and safety of the direct inferior endplate approach in percutaneous endoscopic interlaminar discectomy (PEID) for the treatment of L5-S1 disc herniation.
Methods: This was a retrospective analysis of 116 patients with L5-S1 disc herniation treated with PEID; 74 patients underwent surgery via the direct inferior endplate approach (group A), and 42 patients underwent surgery via the indirect approach (group B). The number of intraoperative fluoroscopy exposures, establishment channel time, operation time, postoperative visual analogue scale (VAS) score, and Oswestry Disability Index (ODI) were compared between the 2 groups.
Nat Commun
January 2025
European Research Institute for the Biology of Ageing, University Medical Center Groningen, Groningen, Netherlands.
While the effect of amplification-induced oncogene expression in cancer is known, the impact of copy-number gains on "bystander" genes is less understood. We create a comprehensive map of dosage compensation in cancer by integrating expression and copy number profiles from over 8000 tumors in The Cancer Genome Atlas and cell lines from the Cancer Cell Line Encyclopedia. Additionally, we analyze 17 cancer open reading frame screens to identify genes toxic to cancer cells when overexpressed.
View Article and Find Full Text PDFEnviron Res
January 2025
Department of Biology, Universidad Autónoma de Madrid, Madrid, Spain. Electronic address:
The negative effects associated with cyanobacterial blooms are of particular concern in protected ecosystems, as these areas are ecologically significant and attract a high number of visitors. This study aims to explore the cyanobacterial communities and associated toxicity in three reservoirs located within a Mediterranean National Park with a compromised situation at basin-level. Our results demonstrate the occurrence of dense toxic blooms containing microcystins (reaching values close to 280 μg L) and low levels of anatoxin-a and saxitoxins (up to 0.
View Article and Find Full Text PDFIntroduction: There is a general impression that patient-based quality control (PBQC) requires a high volume of laboratory results to detect errors effectively. However, internal quality control (IQC) performed infrequently may be associated with increased risk of missed error (i.e.
View Article and Find Full Text PDFVet Immunol Immunopathol
January 2025
Department of Infectious Disease, College of Veterinary Medicine, Seoul National University, Seoul, Korea; Research Institute for Veterinary Science and BK21, Seoul National University, Seoul, Korea. Electronic address:
Background: Bordetella bronchiseptica is a primary pathogen in canine infectious respiratory disease (CIRD), or kennel cough, capable of independently causing respiratory illness and contributing significantly to co-infections with other viral and bacterial agents. Despite its critical role in disease transmission and persistence, the epidemiology of B. bronchiseptica in CIRD remains poorly understood.
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