This study sought to compare the accuracy of two gauges used to alter gutta-percha (GP) cone tips. Randomly selected size 20 cones (with tapers of 0.02, 0.06, 0.10, or 0.12) were trimmed to size 50 (N= 10/taper/gauge) for an overall sample of 80 cones. Accuracy of the altered cone tips was determined by calculating the difference (in %) between the altered tip diameter and the expected tip diameter (0.50 mm). A two-factor ANOVA revealed significant differences (p < or = 0.05) in altered tip accuracy as a result of GP gauge and cone taper. The results suggest that the SybronEndo gauge performs accurately regardless of the cone taper, while the Maillefer gauge was accurate only when used to alter cones with a 0.02 taper.
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Heliyon
January 2025
Environmental Intelligence for Global Change Lab, Department of Electronics, Information and Bioengineering, Politecnico di Milano, Via Ponzio 34/5, 20133, Milan, Italy.
Understanding climate change in a precise and timely manner may assist in gauging the occurrence and seriousness of its impacts, thereby boosting the adaptive capacity and responsiveness of farmers. This investigation looks into farmers' knowledge of climate change, their perception of risks and impacts, and the strategies they anticipate to tackle the challenges of adaptation. A well-structured online survey covering risk awareness, perception, and adaptation was used to randomly sample 460 respondents from 12 irrigation districts in northern Italy.
View Article and Find Full Text PDFPrehosp Disaster Med
January 2025
Assistant Professor, Department of Internal Medicine, UT Southwestern Medical Center, Statistician/Section Chief of Analytics, Research Service, VA North Texas HCS, Dallas, TexasUSA.
Introduction: Terrorism and trauma survivors often experience changes in biomarkers of autonomic, inflammatory and hypothalamic-pituitary-adrenal (HPA) axis assessed at various times. Research suggests interactions of these systems in chronic stress.
Study Objective: This unprecedented retrospective study explores long-term stress biomarkers in three systems in terrorism survivors.
Biology (Basel)
December 2024
Department of Anatomy, Kirksville College of Osteopathic Medicine, Kirksville, MO 63501, USA.
This study was undertaken to explore the forces acting on the pes during pedal anchoring and to discern if pedal anchoring required the activation of the intrinsic pedal musculature. Replica feet equipped with strain gauges were moved over mud substrate, mimicking locomotion and pedal anchoring. Quantification of the substrate tracks demonstrated that they were similar to those made by freely moving , that the locomotor and pedal anchoring tracks were significantly different, and that the composition of the artificial feet significantly altered the tracks.
View Article and Find Full Text PDFHeliyon
December 2024
Baskent University, Faculty of Medicine, Department of Biophysics, Ankara, Türkiye.
The efficacy of MitoTEMPO, a mitochondria-targeted antioxidant, in altering nerve fiber conduction properties within the sciatic nerve of streptozotocin (STZ)-induced diabetic rats, a model for diabetic neuropathy characterized by myelinated fiber atrophy and nodal abnormalities. Utilizing the STZ-induced diabetic rat model, we assessed the impact of MitoTEMPO on nerve function through compound action potential (CAP) analysis and histological evaluation. Key indicators such as maximum depolarization (MD), CAP area, and conduction velocity distribution (CVD) were measured to gauge MitoTEMPO's neuroprotective effects, alongside physical parameters like weight and blood glucose levels.
View Article and Find Full Text PDFJ Cancer
January 2025
Cancer Prevention and Treatment Institute of Chengdu, Department of Neurosurgery, Chengdu Fifth People's Hospital (The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine), Chengdu 611137, China.
Glioblastoma (GBM), notorious for its poor prognosis, stands as a formidable challenge within the central nervous system tumor category, primarily due to its intricate pathology that encompasses stemness and the epithelial-mesenchymal transition (EMT). The ubiquity of S phase kinase-associated protein 2 (Skp2) overexpression in GBM, a protein implicated in both EMT and stemness traits, correlates with increased drug resistance, elevated tumor grades, and adverse outcomes. This investigation delves into the impact of Raddeanin A (RA), a triterpenoid compound extracted from Anemone raddeana Regel, on GBM, with a special focus on its influence over Skp2 expression levels.
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